The Relation of Diabetes, Impaired Fasting Blood Glucose, and Insulin Resistance to Left Ventricular Structure and Function in African Americans The Jackson Heart Study

被引：15
|
作者：
Fox, Ervin R. [1 ]
Sarpong, Daniel F. [2 ]
Cook, Joe C. [1 ]
Samdarshi, Tandaw E. [1 ]
Nagarajarao, Harsha S. [1 ]
Liebson, Philip R. [3 ]
Sims, Mario [1 ]
Howard, George [4 ]
Garrison, Robert [1 ]
Taylor, Herman A., Jr. [1 ]
机构：
[1] Univ Mississippi Sch Med, Jackson, MS 38677 USA
[2] Jackson State Univ, Jackson, MS USA
[3] Rush Univ Med Ctr, Chicago, IL USA
[4] Univ Alabama, Birmingham, AL USA
来源：
DIABETES CARE | 2011年 / 34卷 / 02期
基金：
美国国家卫生研究院;
关键词：
ADULTS;
D O I：
10.2337/dc10-0838
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
OBJECTIVE-We assessed the relation of diabetes and insulin resistance (IR) on left ventricular (LV) structure and function in African Americans. RESEARCH DESIGN AND METHODS-Among those receiving echocardiograms in cycle 1 of the Jackson Heart Study, we assessed the sex-specific relation of fasting blood glucose (FBG), diabetes, and IR to LV structure and function, adjusting for age, systolic blood pressure, antihypertensive medications, and BMI. RESULTS-Among 2,399 participants, LV mass index (P(women) = 0.0002 and P(men) = 0.02), posterior wall thickness (P(women) = 0.01 and P(men) = 0.05), and interventricular septal wall thickness (P(women) = 0.01) were related to FBG categories. Among those with normal FBG and no diabetes, concentric remodeling and low ejection fraction in women and LV mass index and posterior wall thickness in men were related to IR. CONCLUSIONS-In the largest study of its kind in a community-based cohort of African Americans, we found a relation of FBG category and IR to LV structure and function.
引用
收藏
页码：507 / 509
页数：3
相关论文
共 50 条
  • [1] RELATION OF GLUCOSE TOLERANCE AND INSULIN RESISTANCE TO LEFT VENTRICULAR STRUCTURE AND FUNCTION IN AFRICAN AMERICANS (FROM THE JACKSON HEART STUDY)
    Cook, J. C.
    Taylor, H. A.
    Samdarshi, T. E.
    Sarpong, D. F.
    Fox, E. R.
    [J]. JOURNAL OF INVESTIGATIVE MEDICINE, 2009, 57 (01) : 325 - 325
  • [2] IMPACT OF DIABETES AND HYPERTENSION ON LEFT VENTRICULAR STRUCTURE AND FUNCTION IN AFRICAN AMERICANS: THE JACKSON HEART STUDY
    Hamid, A.
    Yimer, W.
    Oshunbade, A. A.
    Kamimura, D.
    Clark, D.
    Fox, E. R.
    Munter, P.
    Shimbo, D.
    Pandey, A.
    Shah, A.
    Min, Y.
    Mentz, R.
    Jones, D.
    Bertoni, A.
    Hall, J. E.
    Correa, A.
    Butler, J.
    Hall, M. E.
    [J]. JOURNAL OF INVESTIGATIVE MEDICINE, 2021, 69 (02) : 449 - 449
  • [3] Epidemiology of retinopathy in African Americans with impaired fasting glucose and type 2 diabetes in the Jackson Heart Study
    Sobrin, Lucia
    Penman, Alan
    Hoadley, Suzanne
    Wilson, James
    Taylor, Herman
    Chen, Ching
    [J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2013, 54 (15)
  • [4] Hypertension and alterations in left ventricular structure and geometry in African Americans: the Jackson Heart Study
    Abdalla, Marwah
    Booth, John N., III
    Diaz, Keith M.
    Sims, Mario
    Muntner, Paul
    Shimbo, Daichi
    [J]. JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION, 2016, 10 (07) : 550 - 558
  • [5] Relation of Left Ventricular Structure to Incident Heart Failure in African Americans: The Jackson Cohort of the Atherosclerosis Risk in Communities Study
    Azeem, Amir
    Beard, Walter L.
    Musani, Solomon
    Butler, Kenneth R.
    Mosley, Thomas H.
    Fox, Ervin R.
    [J]. CIRCULATION, 2016, 133
  • [6] Impact of Diabetes and Hypertension on Left Ventricular Structure and Function: The Jackson Heart Study
    Hamid, Arsalan
    Yimer, Wondwosen K.
    Oshunbade, Adebamike A.
    Kamimura III, Daisuke
    Clark, Donald
    Fox, Ervin R.
    Min, Yuan-, I
    Muntner, Paul
    Shimbo, Daichi
    Pandey, Ambarish
    Shah, Amil M.
    Mentz, Robert J.
    Jones, Daniel W.
    Bertoni, Alain G.
    Hall, John E.
    Correa, Adolfo
    Butler, Javed
    Hall, Michael E.
    [J]. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2023, 12 (06):
  • [7] Left Ventricular Function Across the Spectrum of Body Mass Index in African Americans The Jackson Heart Study
    Patel, Vivek G.
    Gupta, Deepak K.
    Terry, James G.
    Kabagambe, Edmond K.
    Wang, Thomas J.
    Correa, Aldolfo
    Griswold, Michael
    Taylor, Herman
    Jeffrey, John
    [J]. JACC-HEART FAILURE, 2017, 5 (03) : 182 - 190
  • [8] Predictors of Longitudinal Change in Insulin Resistance and Beta-Cell Function in African Americans without Diabetes: The Jackson Heart Study
    Effoe, Valery S.
    Chen, Haiying
    Echouffo-Tcheugui, Justin B.
    Bell, Ronny A.
    Correa, Adolfo
    Joseph, Joshua J.
    Hairston, Kristen G.
    Kalyani, Rita R.
    Bertoni, Alain G.
    [J]. DIABETES, 2016, 65 : A408 - A408
  • [9] Inverse Association of Adiponectin and Left Ventricular Mass in African Americans; The Jackson Heart Study
    Bidulescu, Aurelian
    Liu, Jiankang
    Fox, Ervin R.
    Din-Dzietham, Rebecca
    Samdarshi, Tandaw E.
    Sarpong, Daniel F.
    Vaccarino, Viola
    Wilson, Peter W.
    Arnett, Donna K.
    Taylor, Herman A.
    Gibbons, Gary H.
    [J]. CIRCULATION, 2009, 120 (18) : S544 - S544
  • [10] RELATION OF DIABETES AND IMPAIRED GLUCOSE-TOLERANCE TO LEFT-VENTRICULAR STRUCTURE AND FUNCTION IN ARIZONA-INDIANS - THE STRONG HEART-STUDY
    DEVEREUX, RB
    HOWARD, BV
    ROMAN, MJ
    LEE, ET
    OGRADY, MJ
    FABSITZ, RR
    PARANICAS, M
    YEH, JL
    WELTY, TK
    [J]. CIRCULATION, 1995, 92 (08) : 1997 - 1997
12345