Nick Your DNA, Mark Your Chromatin

被引：0
|
作者：
Nardozza, Aurelio P. [1 ]
Ladurner, Andreas G. [1 ,2 ,3 ]
机构：
[1] Ludwig Maximilians Univ Munchen, Physiol Chem, Biomed Ctr, Grosshaderner St 9, D-82152 Planegg Martinsried, Germany
[2] CIPSM, D-81377 Munich, Germany
[3] Munich Cluster Syst Neurol SyNergy, D-80336 Munich, Germany
来源：
MOLECULAR CELL | 2016年 / 64卷 / 01期
基金：
英国医学研究理事会;
关键词：
PEPTIDES; TARGETS; REVEALS; PARP-1;
D O I：
10.1016/j.molcel.2016.09.023
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
DNA damage induces chemical and structural changes in our chromatin-embedded genome. In a recent issue of Nature Communications, Grundy et al. (2016) identify a role for PARP3 in the repair of single-strand breaks and reveal that PARP3 mono-ADP-ribosylates nucleosomal histone H2B.
引用
收藏
页码：7 / 9
页数：3
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