Stimuli-Responsive Gold Nanocages for Cancer Diagnosis and Treatment

被引:7
|
作者
Li, Chunming [1 ]
Zhao, Tengyue [2 ]
Li, Lixian [1 ]
Hu, Xiaogang [1 ]
Li, Chao [1 ]
Chen, Wanyi [1 ]
Hu, Yurong [2 ]
机构
[1] Chongqing Univ, Dept Pharm, Canc Hosp, 181 Hanyu Rd, Chongqing 400030, Peoples R China
[2] Zhengzhou Univ, Sch Pharmaceut Sci, 100 Kexue Ave, Zhengzhou 450001, Peoples R China
基金
中国国家自然科学基金;
关键词
gold nanocages; stimuli-responsive; controlled release; cancer; diagnosis; treatment; TRIGGERED DRUG-RELEASE; BREAST-CANCER; AU NANOCAGES; TUMOR MICROENVIRONMENT; MESOPOROUS SILICA; FACILE SYNTHESIS; ANTICANCER DRUG; DELIVERY SYSTEM; MESSENGER-RNAS; MOLECULAR GATE;
D O I
10.3390/pharmaceutics14071321
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
With advances in nanotechnology, various new drug delivery systems (DDSs) have emerged and played a key role in the diagnosis and treatment of cancers. Over the last two decades, gold nanocages (AuNCs) have been attracting considerable attention because of their outstanding properties. This review summarizes current advancements in endogenous, exogenous, and dual/multi-stimuli responsive AuNCs in drug delivery. This review focuses on the properties, clinical translation potential, and limitations of stimuli-responsive AuNCs for cancer diagnosis and treatment.
引用
收藏
页数:22
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