Obesity and Postmenopausal Hormone Receptor-positive Breast Cancer: Epidemiology and Mechanisms

被引：1

作者：

Zuo, Qianying ^{[1
]}

Band, Shoham ^{[1
]}

Kesavadas, Mrinali ^{[1
]}

Madak Erdogan, Zeynep ^{[1
,2
,3
,4
,5
]}

机构：

[1] Univ Illinois, Dept Food Sci & Human Nutr, Urbana, IL USA

[2] Univ Illinois, Canc Ctr Illinois, Urbana, IL USA

[3] Univ Illinois, Inst Gen Biol, Urbana, IL USA

[4] Univ Illinois, Div Nutr Sci, Urbana, IL USA

[5] Univ Illinois, Coll Med, Dept Biomed & Translat Sci, Carle Illinois, Urbana, IL USA

来源：

ENDOCRINOLOGY | 2021年 / 162卷 / 12期

关键词：

obesity; estrogen receptor; breast cancer; inflammation; growth factor signaling; BODY-MASS INDEX; FACTOR-BINDING-PROTEINS; FREE FATTY-ACIDS; IGF-I RECEPTOR; ADIPOSE-TISSUE; GROWTH-FACTOR; INSULIN-RESISTANCE; ESTROGEN-RECEPTOR; SEX-HORMONES; LIVER FAT;

D O I：

10.1210/endocr/bqab195

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Obesity is a potential risk for several cancers, including postmenopausal, hormone dependent breast cancers. In this review, we summarize recent studies on the impact of obesity on postmenopausal women's health and discuss several mechanisms that were proposed to increase the risk of breast carcinogenesis.

引用

页数：10

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