A mathematical model for the novel coronavirus epidemic in Wuhan, China

被引:262
|
作者
Yang, Chayu [1 ]
Wang, Jin [1 ]
机构
[1] Univ Tennessee, Dept Math, 615 McCallie Ave, Chattanooga, TN 37403 USA
基金
美国国家卫生研究院;
关键词
COVID-19; compartmental modeling; basic reproduction number; PERSISTENCE; IMPACT;
D O I
10.3934/mbe.2020148
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We propose a mathematical model to investigate the current outbreak of the coronavirus disease 2019 (COVID-19) in Wuhan, China. Our model describes the multiple transmission pathways in the infection dynamics, and emphasizes the role of the environmental reservoir in the transmission and spread of this disease. Our model also employs non-constant transmission rates which change with the epidemiological status and environmental conditions and which reflect the impact of the on-going disease control measures. We conduct a detailed analysis of this model, and demonstrate its application using publicly reported data. Among other findings, our analytical and numerical results indicate that the coronavirus infection would remain endemic, which necessitates long-term disease prevention and intervention programs.
引用
收藏
页码:2708 / 2724
页数:17
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