Introduction Bariatric surgery is recommended as a treatment option in individuals with T2DM and BMI > 35 kg/m(2). However, remission of diabetes following bariatric surgery has varied from 24-73% in various studies. A number of scoring systems have been proposed to predict remission of type 2 diabetes mellitus following bariatric surgery. Out of these ABCD score has shown the most promise. The aims of this study were to analyze the effects of bariatric surgery on T2DM patients and to evaluate the possibility of using ABCD score to help with the patient selection. Material and methods Between 1 January 2016 and 1 December 2017, patients undergoing bariatric surgery for obesity with T2DM were recruited from DMCH Ludhiana and followed up at 3 months and 6 months after surgery for control/remission of diabetes. Results At 6 months, the mean % EWL was 62.74. Significant improvements were noted in FBS (193.05 to 107.97), in HbA1C (8.22 to 6.17), dose of OHAs (1.97 to none), and insulin (32.86 to 5.66). Patients who attained remission were younger, with shorter duration of diabetes and higher C-peptide levels. The preoperative BMI or the % EWL were not predictive of diabetes remission. Higher ABCD scores were significantly associated with higher rates of diabetes remission. Conclusion Bariatric surgery leads to substantial weight loss and amelioration of type 2 diabetes. An ABCD score of > 6 predicts diabetes remission following bariatric surgery, and is recommended as an aid for patient selection and counseling.
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Univ Alcal6, Diabet Obes & Human Reprod Res Grp, Inst Ramon y Cajal Invest Sanitaria IRYCIS, Hosp Univ Ramon y Cajal, E-28034 Madrid, Spain
Ctr Invest Biomed Red Diabet & Enfermedades Metab, E-28029 Madrid, SpainUniv Alcal6, Diabet Obes & Human Reprod Res Grp, Inst Ramon y Cajal Invest Sanitaria IRYCIS, Hosp Univ Ramon y Cajal, E-28034 Madrid, Spain
Insenser, Maria
Vilarrasa, Nuria
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Ctr Invest Biomed Red Diabet & Enfermedades Metab, E-28029 Madrid, Spain
Hosp Univ Bellvitge, Dept Endocrinol & Nutr, E-08907 Barcelona, SpainUniv Alcal6, Diabet Obes & Human Reprod Res Grp, Inst Ramon y Cajal Invest Sanitaria IRYCIS, Hosp Univ Ramon y Cajal, E-28034 Madrid, Spain
Vilarrasa, Nuria
Vendrell, Joan
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Ctr Invest Biomed Red Diabet & Enfermedades Metab, E-28029 Madrid, Spain
Hosp Univ Tarragona Joan XXIII, Inst Invest Sanitaria Pere Virgili, Dept Endocrinol & Nutr, E-43005 Tarragona, SpainUniv Alcal6, Diabet Obes & Human Reprod Res Grp, Inst Ramon y Cajal Invest Sanitaria IRYCIS, Hosp Univ Ramon y Cajal, E-28034 Madrid, Spain
Vendrell, Joan
Escobar-Morreale, Hector F.
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Univ Alcal6, Diabet Obes & Human Reprod Res Grp, Inst Ramon y Cajal Invest Sanitaria IRYCIS, Hosp Univ Ramon y Cajal, E-28034 Madrid, Spain
Ctr Invest Biomed Red Diabet & Enfermedades Metab, E-28029 Madrid, SpainUniv Alcal6, Diabet Obes & Human Reprod Res Grp, Inst Ramon y Cajal Invest Sanitaria IRYCIS, Hosp Univ Ramon y Cajal, E-28034 Madrid, Spain
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Taipei Med Univ, Coll Med Sci & Technol, PhD Program Canc Biol & Drug Discovery, Taipei, Taiwan
Acad Sinica, Taipei, Taiwan
Min Sheng Gen Hosp, Dept Surg, Taipei, TaiwanTaipei Med Univ, Coll Med Sci & Technol, PhD Program Canc Biol & Drug Discovery, Taipei, Taiwan
Chen, Jung-Chien
Hsu, Nan-Yung
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Taipei Med Univ, Coll Med Sci & Technol, PhD Program Canc Biol & Drug Discovery, Taipei, Taiwan
Acad Sinica, Taipei, TaiwanTaipei Med Univ, Coll Med Sci & Technol, PhD Program Canc Biol & Drug Discovery, Taipei, Taiwan
Hsu, Nan-Yung
Lee, Wei-Jei
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Min Sheng Gen Hosp, Dept Surg, Taipei, TaiwanTaipei Med Univ, Coll Med Sci & Technol, PhD Program Canc Biol & Drug Discovery, Taipei, Taiwan
Lee, Wei-Jei
Chen, Shu-Chun
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Min Sheng Gen Hosp, Dept Surg, Taipei, TaiwanTaipei Med Univ, Coll Med Sci & Technol, PhD Program Canc Biol & Drug Discovery, Taipei, Taiwan
Chen, Shu-Chun
Ser, Kong-Han
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Min Sheng Gen Hosp, Dept Surg, Taipei, TaiwanTaipei Med Univ, Coll Med Sci & Technol, PhD Program Canc Biol & Drug Discovery, Taipei, Taiwan
Ser, Kong-Han
Lee, Yi-Chih
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Hsin Univ Sci & Technol, Dept Int Business, Taipei, TaiwanTaipei Med Univ, Coll Med Sci & Technol, PhD Program Canc Biol & Drug Discovery, Taipei, Taiwan
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Min Sheng Gen Hosp, Dept Surg, Tauoyan, Taiwan
Min Sheng Gen Hosp, Ctr Diabet, Tauoyan, TaiwanMin Sheng Gen Hosp, Dept Surg, Tauoyan, Taiwan
Lee, Wei-Jei
Chong, Keong
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Min Sheng Gen Hosp, Ctr Diabet, Tauoyan, TaiwanMin Sheng Gen Hosp, Dept Surg, Tauoyan, Taiwan
Chong, Keong
Ser, Kong-Han
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Min Sheng Gen Hosp, Dept Surg, Tauoyan, Taiwan
Min Sheng Gen Hosp, Ctr Diabet, Tauoyan, TaiwanMin Sheng Gen Hosp, Dept Surg, Tauoyan, Taiwan
Ser, Kong-Han
Chen, Jung-Chien
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Min Sheng Gen Hosp, Dept Surg, Tauoyan, Taiwan
Min Sheng Gen Hosp, Ctr Diabet, Tauoyan, TaiwanMin Sheng Gen Hosp, Dept Surg, Tauoyan, Taiwan
Chen, Jung-Chien
Lee, Yi-Chih
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Ching Yun Univ, Dept Int Business, Zhongli City, Taiwan
Min Sheng Gen Hosp, Ctr Diabet, Tauoyan, TaiwanMin Sheng Gen Hosp, Dept Surg, Tauoyan, Taiwan
Lee, Yi-Chih
Chen, Shu-Chun
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Min Sheng Gen Hosp, Dept Nursing, Tauoyan, Taiwan
Min Sheng Gen Hosp, Ctr Diabet, Tauoyan, TaiwanMin Sheng Gen Hosp, Dept Surg, Tauoyan, Taiwan
Chen, Shu-Chun
Su, Yen-How
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Min Sheng Gen Hosp, Dept Surg, Tauoyan, Taiwan
Min Sheng Gen Hosp, Ctr Diabet, Tauoyan, TaiwanMin Sheng Gen Hosp, Dept Surg, Tauoyan, Taiwan
Su, Yen-How
Tsai, Min-Han
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Min Sheng Gen Hosp, Ctr Diabet, Tauoyan, TaiwanMin Sheng Gen Hosp, Dept Surg, Tauoyan, Taiwan