Guanidine Hydrochloride: A Highly Efficient Organocatalyst for the Synthesis of 12-Aryl-8,9,10,12-tetrahydrobenzo[a]xanthene-11-ones Under Solvent-Free Conditions

被引:18
|
作者
Sadeghpour, Mahdieh [1 ]
Olyaei, Abolfazl [2 ]
Rezaei, Mortaza [2 ]
机构
[1] Islamic Azad Univ, Takestan Branch, Dept Chem, Takestan, Iran
[2] Payame Noor Univ, Dept Chem, POB 19395-3697, Tehran, Iran
关键词
FREE GREEN SYNTHESIS; ONE-POT; DERIVATIVES; CONDENSATION; XANTHENE; ACID;
D O I
10.1002/jhet.1879
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A new green protocol has been developed for the synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthen-11-ones using guanidine hydrochloride as an organocatalyst under solvent-free conditions. Operational simplicity, mild reaction conditions, enhanced rates, high isolated yields of the pure products, and purification of products by nonchromatographic methods are significant advantages of the protocol presented here.
引用
收藏
页码:981 / 988
页数:8
相关论文
共 50 条
  • [1] Synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthene-11-ones catalyzed by biodegradable ionic liquid
    Fang, Dong
    Yang, Jin-ming
    Cao, Yan-fang
    RESEARCH ON CHEMICAL INTERMEDIATES, 2013, 39 (04) : 1745 - 1751
  • [2] Synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthene-11-ones catalyzed by biodegradable ionic liquid
    Dong Fang
    Jin-ming Yang
    Yan-fang Cao
    Research on Chemical Intermediates, 2013, 39 : 1745 - 1751
  • [3] One-pot synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthen-11-ones by using of neutral and efficient organocatalysts under solvent-free conditions
    Reza Heydari
    Fahimeh Shahrekipour
    Research on Chemical Intermediates, 2015, 41 : 4581 - 4586
  • [4] One-pot synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthen-11-ones by using of neutral and efficient organocatalysts under solvent-free conditions
    Heydari, Reza
    Shahrekipour, Fahimeh
    RESEARCH ON CHEMICAL INTERMEDIATES, 2015, 41 (07) : 4581 - 4586
  • [5] Efficient one-pot synthesis of 12-Aryl-8, 9, 10, 12-tetrahydrobenzo[a]xanthen-11-ones under solvent-free conditions
    Xu-dong Jia
    Song-yang Han
    Hai-feng Duan
    Ying-jie Lin
    Jun-gang Cao
    Da-peng Liang
    Mao-cheng Wu
    Chemical Research in Chinese Universities, 2013, 29 : 82 - 86
  • [6] Efficient One-pot Synthesis of 12-Aryl-8, 9, 10, 12-tetrahydrobenzo[a]xanthen-11-ones Under Solvent-free Conditions
    Jia Xu-dong
    Han Song-yang
    Duan Hai-feng
    Lin Ying-jie
    Cao Jun-gang
    Liang Da-peng
    Wu Mao-cheng
    CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2013, 29 (01) : 82 - 86
  • [7] RAPID AND EFFICIENT ONE-POT GREEN SYNTHESIS OF 12-ARYL-8,9,10,12-TETRAHYDROBENZO[a] XANTHENE-11-ONES USING Zr-MCM-41 CATALYST
    Olyaei, Abolfazl
    Alidoust, Mona Ghodrat
    SYNTHETIC COMMUNICATIONS, 2015, 45 (01) : 94 - 104
  • [8] Cu/SiO2-CATALYZED ONE-POT SYNTHESIS OF 12-ARYL-8,9,10,12-TETRAHYDROBENZO[α]XANTHEN-11-ONES UNDER SOLVENT-FREE CONDITIONS
    Oskooie, Hossein A.
    Heravi, Majid M.
    Karimi, Narges
    Kohansal, Golnaz
    SYNTHETIC COMMUNICATIONS, 2011, 41 (18) : 2763 - 2768
  • [9] Organocatalyst trityl chloride efficiently promoted the solvent-free synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]-xanthen-11-ones by in situ formation of carbocationic system in neutral media
    Khazaei, Ardeshir
    Zolfigol, Mohammad Ali
    Moosavi-Zare, Ahmad Reza
    Zare, Abdolkarim
    Khojasteh, Mahmoud
    Asgari, Zhila
    Khakyzadeh, Vahid
    Khalafi-Nezhad, Ali
    CATALYSIS COMMUNICATIONS, 2012, 20 : 54 - 57
  • [10] Synthesis of novel 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthene-11-thiones and evaluation of their biocidal effects
    Khurana, Jitender M.
    Magoo, Devanshi
    Aggarwal, Komal
    Aggarwal, Nisha
    Kumar, Rajesh
    Srivastava, Chitra
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 58 : 470 - 477