MARIMO cells harbor a CALR mutation but are not dependent on JAK2/STAT5 signaling

被引：28
|
作者：
Kollmann, K. [1 ,2 ]
Nangalia, J. [1 ,2 ,3 ,4 ]
Warsch, W. [1 ,2 ]
Quentmeier, H. [5 ]
Bench, A. [4 ]
Boyd, E. [4 ]
Scott, M. [4 ]
Drexler, H. G. [5 ]
Green, A. R. [1 ,2 ,4 ]
机构：
[1] Univ Cambridge, Wellcome Trust MRC Stem Cell Inst, Cambridge Inst Med Res, Cambridge, England
[2] Univ Cambridge, Dept Haematol, Cambridge, England
[3] Wellcome Trust Sanger Inst, Cambridge, England
[4] Cambridge Univ Hosp NHS Fdn Trust, Cambridge, England
[5] German Collect Microorganisms & Cell Cultures, Leibniz Inst DSMZ, Braunschweig, Germany
来源：
LEUKEMIA | 2015年 / 29卷 / 02期
关键词：
MYELOPROLIFERATIVE NEOPLASMS; ESSENTIAL THROMBOCYTHEMIA; MYELOFIBROSIS; RETICULUM; JAK2; CALRETICULIN; INHIBITOR;
D O I：
10.1038/leu.2014.285
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
下载
收藏
页码：494 / 497
页数：5
相关论文
共 50 条
  • [1] MARIMO cells harbor a CALR mutation but are not dependent on JAK2/STAT5 signaling
    K Kollmann
    J Nangalia
    W Warsch
    H Quentmeier
    A Bench
    E Boyd
    M Scott
    H G Drexler
    A R Green
    Leukemia, 2015, 29 : 494 - 497
  • [2] In vitro interaction between STAT5 and JAK2;: dependence upon phosphorylation status of STAT5 and JAK2
    Flores-Morales, A
    Pircher, TJ
    Silvennoinen, O
    Gustafsson, JÅ
    Sanchez-Gomez, M
    Norstedt, G
    Haldosén, LA
    Wood, TJJ
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1998, 138 (1-2) : 1 - 10
  • [3] Mutant NRAS Q61K is responsible for MAPK pathway activation in the MARIMO cell line and renders these cells independent of the CALR–MPL–JAK2–STAT5 pathway
    Lijuan Han
    Julia Czech
    Angela Maurer
    Tim H. Brümmendorf
    Nicolas Chatain
    Steffen Koschmieder
    Leukemia, 2018, 32 : 2087 - 2090
  • [4] Jak2/Stat5 Signaling in Mammogenesis, Breast Cancer Initiation and Progression
    Kay-Uwe Wagner
    Hallgeir Rui
    Journal of Mammary Gland Biology and Neoplasia, 2008, 13 : 93 - 103
  • [5] Jak2/Stat5 signaling in mammogenesis, breast cancer initiation and progression
    Wagner, Kay-Uwe
    Rui, Hallgeir
    JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, 2008, 13 (01) : 93 - 103
  • [6] JAK2/STAT5 Signaling Pathway Mediates Bojungbangdocktang enhanced Hematopoiesis
    Lim, Jeonghan
    Jeong, Soo-Jin
    Koh, Wonil
    Han, Ihn
    Lee, Hyo-Jung
    Kwon, Tae-Rin
    Jung, Ji Hoon
    Kim, Jung Hyo
    Lee, Hyo-Jeong
    Lee, Eun-Ok
    Kim, Sun-Hyung
    Lee, Min-Ho
    Kim, Sung-Hoon
    PHYTOTHERAPY RESEARCH, 2011, 25 (03) : 329 - 337
  • [7] JAK2/STAT5 signaling in the lipopolysaccharide (LPS)-induced inhibition of osteoblast differentiation
    Wu, Hao
    Liu, Guanghui
    Yu, Bin
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2016, 9 (11): : 11119 - 11128
  • [8] Effect of GJIC modulation on Jak2/STAT5 in mammary cells in vitro
    Talhouk, RS
    Ismail, A
    Zeytouni, T
    El-Sabban, ME
    MOLECULAR BIOLOGY OF THE CELL, 2002, 13 : 491A - 491A
  • [9] The JAK2/STAT5 signaling pathway as a potential therapeutic target in canine mastocytoma
    Keller, Alexandra
    Wingelhofer, Bettina
    Peter, Barbara
    Bauer, Karin
    Berger, Daniela
    Gamperl, Susanne
    Reifinger, Martin
    Cerny-Reiterer, Sabine
    Moriggl, Richard
    Willmann, Michael
    Valent, Peter
    Hadzijusufovic, Emir
    VETERINARY AND COMPARATIVE ONCOLOGY, 2018, 16 (01) : 55 - 68
  • [10] Prolactin regulates ZNT2 expression through the JAK2/STAT5 signaling pathway in mammary cells
    Qian, Linxi
    Lopez, Veronica
    Seo, Young Ah
    Kelleher, Shannon L.
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2009, 297 (02): : C369 - C377
12345