HuMax-CD20, a novel fully human anti-CD20 monoclonal antibody: Results of a phase I/II trial in relapsed or refractory follicular non-Hodgkins's lymphoma.

被引:0
|
作者
Hagenbeek, A
Plesner, T
Johnson, P
Pedersen, L
Walewski, J
Hellmann, A
Link, B
Robak, T
Wojtukiewicz, M
Pfreundschuh, M
Kneba, M
Engert, A
Sonneveld, P
Petersen, J
Radford, J
机构
[1] Univ Med Ctr, Utrecht, Netherlands
[2] Vejle Hosp, Vejle, Denmark
[3] Southampton Gen Hosp, Southampton, Hants, England
[4] KAS Herlev, Herlev, Denmark
[5] MSCM Canc Ctr, Warsaw, Poland
[6] Klin Hematol Akad Med, Gdansk, Poland
[7] Univ Iowa, Iowa City, IA 52242 USA
[8] Med Univ Lodz, Lodz, Poland
[9] Oddzial Chemioterapii Bialostocki, Bialystok, Poland
[10] Univ Saarlandes Kliniken, Saarbrucken, Germany
[11] Univ Klinikum Schleswig Holstein, Kiel, Germany
[12] Univ Hosp, Cologne, Germany
[13] Erasmus Med Ctr, Rotterdam, Netherlands
[14] Genmab AS, Copenhagen, Denmark
[15] Christie Hosp NHS Trust, Manchester M20 4BX, Lancs, England
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
4760
引用
收藏
页码:270B / 270B
页数:1
相关论文
共 50 条
  • [1] HuMax-CD20 fully human monoclonal antibody in follicular lymphoma. First human exposure: Early results of an ongoing phase I/II trial.
    Hagenbeek, A
    Plesner, T
    Walewski, J
    Hellmann, A
    Link, BK
    Dalby, LW
    [J]. BLOOD, 2004, 104 (11) : 393A - 393A
  • [2] Radioimmunotherapy with 131I anti-CD20 chimeric monoclonal antibody (rituximab) for relapsed or refractory non-Hodgkins lymphoma.
    Turner, JH
    Martindale, A
    Claringbold, PG
    Boucek, J
    Leahy, MF
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2002, 43 (05) : 115P - 116P
  • [3] First clinical use of ofatumumab, a novel fully human anti-CD20 monoclonal antibody in relapsed or refractory follicular lymphoma: results of a phase 1/2 trial
    Hagenbeek, Anton
    Gadeberg, Ole
    Johnson, Peter
    Pedersen, Lars Moller
    Walewski, Jan
    Hellmann, Andrzej
    Link, Brian K.
    Robak, Tadeusz
    Wojtukiewicz, Marek
    Pfreundschuh, Michael
    Kneba, Michael
    Engert, Andreas
    Sonneveld, Pieter
    Flensburg, Mimi
    Petersen, Jorgen
    Losic, Nedjad
    Radford, John
    [J]. BLOOD, 2008, 111 (12) : 5486 - 5495
  • [4] Results of a phase I/II study of ocrelizumab, a fully humanized anti-CD20 mAb, in patients with relapsed/refractory follicular lymphoma
    Morschhauser, F.
    Marlton, P.
    Vitolo, U.
    Linden, O.
    Seymour, J. F.
    Crump, M.
    Coiffier, B.
    Foa, R.
    Wassner, E.
    Burger, H. -U.
    Brennan, B.
    Mendila, M.
    [J]. ANNALS OF ONCOLOGY, 2010, 21 (09) : 1870 - 1876
  • [5] A novel fully human anti-CD20 monoclonal antibody. First clinical results from an ongoing phase I/II trial in patients with follicular non-Hodgkin's lymphoma
    Hagenbeek, A
    Plesner, T
    Walewski, J
    Kneba, M
    Petersen, J
    Radford, J
    [J]. ANNALS OF ONCOLOGY, 2005, 16 : 71 - 71
  • [7] Interim results of a phase I/II study of ocrelizumab, a new humanised Anti-CD20 antibody in patients with relapsed/refractory follicular non-hodgkin's lymphoma
    Morschhauser, Franck
    Marlton, Paula
    Vitolo, Umberto
    Linden, Ola
    Seymour, John
    Crump, Michael
    Coiffier, Bertrand
    Pulsoni, Alessandro
    Belch, Andrew
    Lerch, Erika
    Kimby, Eva
    Arnljots, Kristina
    Wassner, Elisabeth
    Mendila, Myriam
    [J]. BLOOD, 2007, 110 (11) : 199A - 199A
  • [8] Humanized Anti-CD20 Antibody, Veltuzumab, in Refractory/Recurrent Non-Hodgkin's Lymphoma: Phase I/II Results
    Morschhauser, Franck
    Leonard, John P.
    Fayad, Luis
    Coiffier, Bertrand
    Petillon, Marie-Odile
    Coleman, Morton
    Schuster, Stephen J.
    Dyer, Martin J. S.
    Horne, Heather
    Teoh, Nick
    Wegener, William A.
    Goldenberg, David M.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (20) : 3346 - 3353
  • [9] HuMax-CD20, a novel fully human monoclonal IgG1 antibody in the treatment of rheumatoid arthritis.
    Ostergaard, M.
    Wiell, C.
    Sierakowski, S.
    Wallace, D.
    Kastberg, H.
    Petersen, J.
    Dawes, P. T.
    [J]. ARTHRITIS AND RHEUMATISM, 2006, 54 (09): : S832 - S832
  • [10] First clinical results of HuMax-CD20 fully human monoclonal IGG1 antibody treatment in rheumatoid arthritis
    Ostergaard, M.
    Wiell, C.
    Dawes, P. T.
    Rigby, W.
    Petersen, J.
    Kastberg, H.
    Sierakowski, S.
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 2006, 65 : 58 - 59