Changing epidemiology of hepatitis C virus genotypes in the central region of Argentina

被引：3
|
作者：
Alejandro Di Lello, Federico [1 ,2 ]
Alejandro Farias, Adrian [3 ]
Alberto Culasso, Andres Carlos [1 ,2 ]
Soledad Perez, Paula [1 ]
Belen Pisano, Maria [3 ]
Silvia Contigiani, Marta [3 ]
Hector Campos, Rodolfo [1 ,2 ]
Elizabeth Re, Viviana [2 ,3 ]
机构：
[1] Univ Buenos Aires, Fac Farm & Bioquim, Catedra Virol, RA-1113 Buenos Aires, DF, Argentina
[2] Consejo Nacl Invest Cient & Tecn, RA-1033 Buenos Aires, DF, Argentina
[3] Univ Nacl Cordoba, Fac Ciencias Med, Inst Virol Dr JM Vanella, Lab Hepatitis & Arbovirus, RA-5016 Cordoba, Argentina
来源：
ARCHIVES OF VIROLOGY | 2015年 / 160卷 / 04期
关键词：
HIGH PREVALENCE; 1B; INFECTION; DIVERSITY; 1A;
D O I：
10.1007/s00705-015-2390-6
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The aim of this study was to analyze the prevalence of hepatitis C virus (HCV) genotypes in Cordoba province, Argentina, over a 12-year period and to study the changes at the molecular level. The HCV genotype was determined in 357 HCV-infected patients, and the phylogeny and demographic reconstruction for HCV-1 was assessed. A significant reduction in HCV-2 prevalence with respect to HCV-1 in Cordoba after 2003 was observed. These findings are consistent with the epidemiological changes observed in South America. Nevertheless, the consequences of these changes remain to be elucidated.
引用
收藏
页码：909 / 915
页数：7
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