Wound healing through synergy of hyaluronan and an iodine complex

被引:14
|
作者
Cutting, K. F. [1 ,2 ]
机构
[1] Buckinghamshire New Univ, Uxbridge, Middx, England
[2] Perfectus Med Ltd, Daresbury, England
关键词
Hyaluronan; moist wound healing; antimicrobial; iodine: tri-iodide; FREE-RADICAL DAMAGE; POVIDONE-IODINE; ANGIOGENIC OLIGOSACCHARIDES; GRANULATION-TISSUE; CELL-MIGRATION; ACID; FIBROBLASTS; INHIBITION; EXPRESSION; TOXICITY;
D O I
10.12968/jowc.2011.20.9.424
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Hyaluronan, a glycosaminoglycan (GAG), is a polysaccharide found in many locations in the human body, such as eye, skin and soft tissue. It is also found in other mammals and bacteria. As a component of the extracellular matrix, its role in wound repair, among others, is that of providing a temporary structure to support new tissue formation. Harnessing the therapeutic action of hyaluronan into a topical application of proven clinical benefit has proved challenging. A new development in hyaluronan technology, comprising sodium hyaluronate and iodine complex, offers a novel approach in exploiting the benefits of hyaluronan and delivering real clinical benefits for a wide range of wound types.
引用
收藏
页码:424 / +
页数:5
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