Seeds of Destruction: New Mechanistic Insights into the Role of Apolipoprotein E4 in Alzheimer's Disease

被引：3
|
作者：
Vassar, Robert [1 ]
机构：
[1] Northwestern Univ, Dept Cell & Mol Biol, Feinberg Sch Med, Chicago, IL 60611 USA
来源：
NEURON | 2017年 / 96卷 / 05期
关键词：
GENOTYPE;
D O I：
10.1016/j.neuron.2017.11.022
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Apolipoprotein E4 (apoE4) is the strongest genetic risk factor for Alzheimer's disease. Despite nearly 25 years of research, the mechanism by which apoE4 confers increased risk for Alzheimer's disease remains enigmatic. In this issue of Neuron, Liu et al. (2017) and Huynh et al. (2017) shed new light on this important question.
引用
收藏
页码：953 / 955
页数：4
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