Microenvironmental Interleukin-6 induced activation of STAT3 signaling in medulloblastoma: Implications for molecular pathology and therapy

被引：0
|
作者：
Yan, Shuang
Chatterjee, Sampurna
Vardam, Trupti
Kitahara, Shuji
Hato, Tai
Roberge, Sylvie
Askoxylakis, Vasileios
Duquette, Mark
Fukumura, Dai
Xu, Lei
Jain, Rakesh
机构：
[1] Massachusetts Gen Hosp, Boston, MA 02114 USA
[2] Harvard Univ, Sch Med, Boston, MA USA
来源：
CANCER RESEARCH | 2016年 / 76卷
关键词：
D O I：
10.1158/1538-7445.PEDCA15-A12
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
A12
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Activation of Interleukin-6/STAT3 in Rat Cholangiocyte Proliferation Induced by Lipopolysaccharide
    Li-Ping Chen
    Ming Cai
    Qi-Hao Zhang
    Zhou-Li Li
    Ye-Yong Qian
    Hong-Wei Bai
    Xing Wei
    Bing-Yi Shi
    Jia-Hong Dong
    Digestive Diseases and Sciences, 2009, 54 : 547 - 554
  • [2] Activation of Interleukin-6/STAT3 in Rat Cholangiocyte Proliferation Induced by Lipopolysaccharide
    Chen, Li-Ping
    Cai, Ming
    Zhang, Qi-Hao
    Li, Zhou-
    Qian, Ye-Yong
    Bai, Hong-Wei
    Wei, Xing
    Shi, Bing-Yi
    Dong, Jia-Hong
    DIGESTIVE DISEASES AND SCIENCES, 2009, 54 (03) : 547 - 554
  • [3] Inhibition of interleukin-6 signaling and Stat3 activation by a new class of bioactive cyclopentenone derivatives
    Weidler, M
    Rether, J
    Anke, T
    Erkel, G
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2000, 276 (02) : 447 - 453
  • [4] Activation of interleukin-6/STAT3 and liver regeneration following transplantation
    Debonera, F
    Aldeguer, X
    Shen, XD
    Gelman, AE
    Gao, F
    Que, XY
    Greenbaum, LE
    Furth, EE
    Taub, R
    Olthoff, KM
    JOURNAL OF SURGICAL RESEARCH, 2001, 96 (02) : 289 - 295
  • [5] Interleukin-6 induces prostate cancer cell growth accompanied by activation of Stat3 signaling pathway
    Lou, W
    Ni, ZY
    Dyer, K
    Tweardy, DJ
    Gao, AC
    PROSTATE, 2000, 42 (03): : 239 - 242
  • [6] Predominant Activation of JAK/STAT3 Pathway by Interleukin-6 Is Implicated in Hepatocarcinogenesis
    Jung, In Hye
    Choi, Jeffrey Hyun-Kyu
    Chung, Yong-Yoon
    Lim, Ga-Lam
    Park, Young-Nyun
    Park, Seung Woo
    NEOPLASIA, 2015, 17 (07): : 586 - 597
  • [7] Blocking interleukin-6 trans-signaling protects against renal fibrosis by suppressing STAT3 activation
    Chen, Wei
    Yuan, Hui
    Cao, Wenmin
    Wang, Tianwei
    Chen, Wei
    Yu, Hang
    Fu, Yao
    Jiang, Bo
    Zhou, Hong
    Guo, Hongqian
    Zhao, Xiaozhi
    THERANOSTICS, 2019, 9 (14): : 3980 - 3991
  • [8] INTERLEUKIN-6 TRANS SIGNALING AND STAT3 ACTIVATION PROMOTE NEUTROPHILIC INFLAMMATION IN ALCOHOL-ASSOCIATED HEPATITIS
    Rachakonda, Vikrant
    Sarode, Gaurav
    Argemi, Josepmaria
    Bataller, Ramon
    GASTROENTEROLOGY, 2024, 166 (05) : S1670 - S1671
  • [9] Interleukin-6/STAT3 Pathway Signaling Drives an Inflammatory Phenotype in Group A Ependymoma
    Griesinger, Andrea M.
    Josephson, Rebecca J.
    Donson, Andrew M.
    Levy, Jean M. Mulcahy
    Amani, Vladimir
    Birks, Diane K.
    Hoffman, Lindsey M.
    Furtek, Steffanie L.
    Reigan, Phillip
    Handler, Michael H.
    Vibhakar, Rajeev
    Foreman, Nicholas K.
    CANCER IMMUNOLOGY RESEARCH, 2015, 3 (10) : 1165 - 1174
  • [10] Interleukin-6/STAT3 signaling as a promising target to improve the efficacy of cancer immunotherapy
    Kitamura, Hidemitsu
    Ohno, Yosuke
    Toyoshima, Yujiro
    Ohtake, Junya
    Homma, Shigenori
    Kawamura, Hideki
    Takahashi, Norihiko
    Taketomi, Akinobu
    CANCER SCIENCE, 2017, 108 (10): : 1947 - 1952
12345