Chemical constituents of Impatiens chapaensis Tard. and their α-glucosidase inhibition activities

被引：4

作者：

Linh, Nguyen Thi Thuy ^{[1
,2
]}

Thuy, Trinh Thi ^{[1
,2
]}

Tam, Nguyen Thanh ^{[2
]}

Cham, Ba Thi ^{[1
,2
]}

Tam, Khieu Thi ^{[3
]}

Sa, Nguyen Hoang ^{[4
]}

Thao, Do Thi ^{[5
]}

Chinh, Vu Tien ^{[1
,6
]}

Anh, Nguyen Thi Hoang ^{[1
,2
]}

机构：

[1] Grad Univ Sci & Technol, Vietnam Acad Sci & Technol, Hanoi, Vietnam

[2] Vietnam Acad Sci & Technol, Inst Chem, Hanoi, Vietnam

[3] Univ Thai Nguyen, Thai Nguyen, Vietnam

[4] Univ Khanh Hoa, Nha Trang, Khanh Hoa, Vietnam

[5] Vietnam Acad Sci & Technol, Inst Biotechnol, Hanoi, Vietnam

[6] Vietnam Acad Sci & Technol, Vietnam Natl Museum Nat, Hanoi, Vietnam

来源：

NATURAL PRODUCT RESEARCH | 2022年 / 36卷 / 12期

关键词：

Impatiens chapaensis; Balsaminaceae; flavonoid glycoside; sesquiterpene; neolignan glycoside; COMPOUND;

D O I：

10.1080/14786419.2021.1956923

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Sixteen compounds (1-16) were isolated from Impatiens chapaensis. Chemical structures were determined by spectroscopic analyses and comparisons with previously published data. This report is the first to identify compounds 1, 5-7, 10, 12-14, and 16 from the genus Impatiens. Seven chosen isolates (5, 7, 10, 11, 12, 15, and 16) were submitted for alpha-glucosidase inhibition assays with acarbose as the positive control (IC50 = 227.14 +/- 13.71 mu M). Flavonoid 5 exhibited a significant inhibitory effect (IC50 = 101.00 +/- 9.01 mu M).

引用

页码：3229 / 3233

页数：5

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