Synthesis of some functionalized arylaminomethyl-1,2,4-triazoles, 1,3,4-oxa- and thiadiazoles

被引：0
|
作者：
Abdel-Aal, MT [1 ]
El-Sayed, WA
Aleem, AHA
EL Ashry, ESH
机构：
[1] Menoufia Univ, Fac Sci, Dept Chem, El Koam, Egypt
[2] Univ Alexandria, Fac Sci, Alexandria, Egypt
[3] Univ Alexandria, Fac Sci, Dept Chem, Alexandria, Egypt
来源：
PHARMAZIE | 2003年 / 58卷 / 11期
关键词：
D O I：
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中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Thiosemicarbazides undergo different cyclization reactions to give five membered heterocycles. The product of cyclization depends on the reagent used. This cyclization leads to the formation of 1,3,4-oxadiazole, 1,3,4-thiadiazole and 1,2,4-triazole derivatives. The reaction of thioglycolyl hydrazide derivatives of the 1,2,4-triazole compounds was discussed. The activity against hepatitis B virus (HBV) has been tested.
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页码：788 / 792
页数：5
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