HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS IN CHILDREN WITH VISCERAL LEISHMANIASIS

被引：21

作者：

Blazquez-Gamero, Daniel ^{[1
]}

Dominguez-Pinilla, Nerea ^{[2
]}

Chicharro, Carmen ^{[3
]}

Negreira, Sagrario ^{[1
]}

Galan, Pilar ^{[4
]}

Perez-Gorricho, Beatriz ^{[5
]}

Calvo, Cristina ^{[6
]}

Prieto, Luis ^{[7
]}

De la Parte, Maria ^{[8
]}

Otheo, Enrique ^{[9
]}

Luis Vivanco, Jose ^{[2
]}

Ruiz-Contreras, Jesus ^{[1
]}

机构：

[1] 12 Octubre Univ Hosp, Pediat Infect Dis & Immunodeficiencies Unit, Madrid, Spain

[2] 12 Octubre Univ Hosp, Pediat Hematol Oncol Unit, Madrid, Spain

[3] Inst Salud Carlos III, Ctr Nacl Microbiol, WHO Collaborating Ctr Leishmaniasis, Serv Parasitol, Madrid, Spain

[4] Fuenlabrada Univ Hosp, Dept Pediat, Fuenlabrada, Spain

[5] Hosp Infantil Univ Nino Jesus, Pediat Infect Dis Unit, Madrid, Spain

[6] Severo Ochoa Univ Hosp, Dept Pediat, Leganes, Spain

[7] Getafe Univ Hosp, Dept Pediat, Getafe, Spain

[8] Mostoles Univ Hosp, Dept Pediat, Mostoles, Spain

[9] Ramon y Cajal Univ Hosp, Dept Pediat, Madrid, Spain

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2015年 / 34卷 / 06期

关键词：

Hemophagocytic lymphohistiocytosis; hemophagocytosis; visceral leishmaniasis; Leishmania infantum; children; ASSOCIATION; SPAIN;

D O I：

10.1097/INF.0000000000000685

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Acquired hemophagocytic lymphohistiocitosis (HLH) syndrome can be a complication of visceral leishmaniasis (VL). A multicenter prospective study was conducted to determine the frequency of HLH syndrome in children with VL. Twenty-four children with VL were identified, and 10 (41%) developed HLH syndrome. VL should be ruled out in all children with HLH criteria living in or coming from endemic areas.

引用

页码：667 / 669

页数：3

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