Hypercoagulability of COVID-19 and Neurological Complications: A Review

被引：7
|
作者：
Moore, Patrick [1 ]
Esmail, Fatema [1 ]
Qin, Shuai [1 ]
Nand, Sucha [1 ,2 ]
Berg, Stephanie [3 ,4 ]
机构：
[1] Loyola Univ Med Ctr, Dept Inter Med, Div Hematol & Oncol, Maywood, IL 60153 USA
[2] Loyola Univ Med Ctr, Dept Internal Med Neurol, Div Hematol & Oncol, Loyola Univ Chicago Prof Internal Med, Maywood, IL USA
[3] Loyola Univ Med Ctr, Dept Internal Med, Div Hematol & Oncol, Loyola Univ Chicago Assistant Prof Med, Maywood, IL USA
[4] Loyola Univ Med Ctr, Dept Canc Biol, Maywood, IL 60153 USA
来源：
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES | 2022年 / 31卷 / 01期
关键词：
COVID-19; Anticoagulation; SARS-CoV-2; Neurologic outcomes; ENDOTHELIAL GLYCOCALYX; HEPARAN-SULFATE; DISEASE; BINDING; RISK; THROMBOCYTOPENIA; INTERLEUKIN-8; COAGULATION; INFECTIONS; MECHANISMS;
D O I：
10.1016/j.jstrokecerebrovasdis.2021.106163
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The SARS-CoV-2 virus, which causes Coronavirus disease 2019 (COVID-19), has resulted in millions of worldwide deaths. When the SARS-CoV-2 virus emerged from Wuhan, China in December 2019, reports of patients with COVID-19 revealed that hospitalized patients had acute changes in mental status, cognition, and encephalopathy. Neurologic complications can be a consequence from overall severity of the systemic infection, direct viral invasion of the SARS-CoV-2 virus in the central nervous system, and possible immune mediated mechanisms. We will examine the landscape regarding this topic in this review in addition to current understandings of COVID-19 and hemostasis, treatment, and prevention, as well as vaccination.
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页数：19
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