Moderate consumption of alcohol-free red wine provide more beneficial effects on systemic haemodynamics, lipid profile and oxidative stress in spontaneously hypertensive rats than red wine

被引：9

作者：

Mihailavic-Stanojevic, Nevena ^{[1
]}

Savikin, Katarina ^{[2
]}

Zivkovic, Jelena ^{[2
]}

Zdunic, Gordana ^{[2
]}

Miloradovic, Zoran ^{[1
]}

Ivanov, Milan ^{[1
]}

Karanovic, Danijela ^{[1
]}

Vajic, Una-Jovana ^{[1
]}

Jovovic, Djurdjica ^{[1
]}

Grujic-Milanovic, Jelica ^{[1
]}

机构：

[1] Univ Belgrade, Inst Med Res, Dr Subotica 4, Belgrade 11000, Serbia

[2] Inst Med Plant Res Dr Josif Pancic, Tadeusa Koscuska 1, Belgrade 11000, Serbia

来源：

JOURNAL OF FUNCTIONAL FOODS | 2016年 / 26卷

关键词：

Alcohol-free red wine; Anthocyanins; Malvidin-3-O-glucoside; Blood pressure; Oxidative stress; Magnesium; RADICAL SCAVENGING ACTIVITY; PHENOLIC COMPOSITION; BLOOD-PRESSURE; SPECTROPHOTOMETRIC METHODS; ANTIOXIDANT ACTIVITIES; ANTHOCYANIN PROFILES; CABERNET-SAUVIGNON; NITRIC-OXIDE; GRAPE; POLYPHENOLS;

D O I：

10.1016/j.jff.2016.08.051

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Numerous studies have shown that moderate wine consumption is associated with decreased incidence of cardiovascular disease, including hypertension. Others observed that moderate alcohol consumption lowers the risk of cardiovascular events. The aim of the present study was to identify and quantify the components of red wine (RW) and alcohol-free red wine (AFRW), and compare the effects of their 4-week consumption (1 mL/day) on haemodynamics, lipid profile and oxidative stress in adult male spontaneously hypertensive rats (SHR). Among anthocyanins, malvidin 3-O-glucoside dominates in both RW and AFRW. AFRW reduces blood pressure of SHR. Both RW and AFRW can increase antioxidant capacity and reduce susceptibility of plasma to lipid peroxidation. RW, due to adverse triacylglycerol levels elevates the risk of cardiovascular complications in SHR. Removing alcohol from wine eliminates these adverse effects and promotes AFRW as a useful beverage in hypertensive patients. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：719 / 730

页数：12

共 2 条

[1] EFFECTS OF REGULAR CONSUMPTION OF RED WINE AND ALCOHOL-FREE RED WINE ON SYSTEMIC HAEMODYNAMICS, LIPID PROFILE AND OXIDATIVE STRESS IN SPONTANEOUSLY HYPERTENSIVE RATS
Mihailovic-Stanojevic, N.
Savikin, K.
Miloradovic, Z.
Ivanov, M.
Karanovic, D.
Vajic, U. J.
Jovovic, D.
Grujic-Milanovic, J.
[J]. JOURNAL OF HYPERTENSION, 2016, 34 : E317 - E317
[2] Red wine but not alcohol consumption improves cardiovascular function and oxidative stress of the hypertensive-SHR and diabetic-STZ rats
Souza Bomfim, Guilherme Henrique
Musial, Diego Castro
Rocha, Katiucha
Jurkiewicz, Aron
Jurkiewicz, Neide Hyppolito
[J]. CLINICAL AND EXPERIMENTAL HYPERTENSION, 2022, 44 (06) : 573 - 584

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