Reaction of (het)aryl cyclohexyl ketoximes with acetylene in the two-phase KOH/DMSO/n-hexane system: en route to spirocyclic 3H-pyrroles

被引：5

作者：

Shabalin, Dmitrii A. ^{[1
]}

Dvorko, Marina Yu ^{[1
]}

Schmidt, Elena Yu ^{[1
]}

Protsuk, Nadezhda I. ^{[1
]}

Ushakov, Igor A. ^{[1
]}

Mikhaleva, Al'bina I. ^{[1
]}

Trofimov, Boris A. ^{[1
]}

机构：

[1] Russian Acad Sci, Siberian Branch, AE Favorsky Irkutsk Inst Chem, Irkutsk 664033, Russia

来源：

MENDELEEV COMMUNICATIONS | 2015年 / 25卷 / 02期

基金：

俄罗斯基础研究基金会;

关键词：

SPIRO HETEROCYCLIZATION; 4,5-DIAROYL-1H-PYRROLE-2,3-DIONES; 3-DIAZOPYRROLES;

D O I：

10.1016/j.mencom.2015.03.017

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cyclohexyl phenyl and cyclohexyl (2-thienyl) ketoximes react with acetylene under pressure in the two-phase KOH/DMSO/n-hexane system at 70 degrees C to afford the corresponding spirocyclic 3H-pyrroles, 1-(het)aryl-2-azaspiro[4.5]deca-1,3-dienes, in 18-19% yields.

引用

页码：129 / 130

页数：2

共 2 条

[1] Formation of 2-ethynyl-3,4-dihydro-2H-pyrroles in the synthesis of 3H-pyrroles from ketoximes and acetylene in the system KOH—DMSO—hexane
D. A. Shabalin
E. Yu. Schmidt
M. Yu. Dvorko
N. I. Protsuk
I. A. Ushakov
B. A. Trofimov
Russian Journal of Organic Chemistry, 2015, 51 : 1346 - 1348
[2] Formation of 2-ethynyl-3,4-dihydro-2H-pyrroles in the synthesis of 3H-pyrroles from ketoximes and acetylene in the system KOH-DMSO-hexane
Shabalin, D. A.
Schmidt, E. Yu.
Dvorko, M. Yu.
Protsuk, N. I.
Ushakov, I. A.
Trofimov, B. A.
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2015, 51 (09) : 1346 - 1348

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