Human Norovirus as a Foodborne Pathogen: Challenges and Developments

被引:81
|
作者
Moore, Matthew D. [1 ]
Goulter, Rebecca M. [1 ]
Jaykus, Lee-Ann [1 ]
机构
[1] N Carolina State Univ, Dept Food Bioproc & Nutr Sci, Raleigh, NC 27695 USA
关键词
epidemiology; detection; evolution; cell culture; infectivity; NORWALK-LIKE VIRUS; INFECTIOUS INTESTINAL DISEASE; GROUP ANTIGEN-EXPRESSION; HUMAN GII.4 NOROVIRUS; BLOOD GROUP ANTIGENS; TIME RT-PCR; UNITED-STATES; MURINE NOROVIRUS; FELINE CALICIVIRUS; PROPIDIUM MONOAZIDE;
D O I
10.1146/annurev-food-022814-015643
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Human noroviruses (NoVs) are the leading cause of foodborne illness in the United States, and they exact a considerable human and economic burden worldwide. In fact, the many challenging aspects of human NoV have caused some to call it the nearly perfect foodborne pathogen. In this review, a brief overview of NoVs and their genetic structure is provided. Additionally, the challenges and recent developments related to human NoVs regarding viral evolution, transmission, epidemiology, outbreak identification, cultivation, animal and human models, and detection are presented.
引用
收藏
页码:411 / 433
页数:23
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