Validation of a Model Predicting Anti-infective Lung Penetration in the Epithelial Lining Fluid of Humans

被引:5
|
作者
Aulin, Linda B. S. [1 ]
Valitalo, Pyry A. [2 ]
Rizk, Matthew L. [3 ]
Visser, Sandra A. G. [4 ]
Rao, Gauri [5 ]
van der Graaf, Piet H. [1 ,6 ]
van Hasselt, J. G. Coen [1 ]
机构
[1] Leiden Univ, Leiden Acad Ctr Drug Res, Einsteinweg 55, NL-2333 CC Leiden, Netherlands
[2] Orion Corp Orion Pharma, Kuopio, Finland
[3] Merck & Co Inc, Kenilworth, NJ USA
[4] GSK, King Of Prussia, PA USA
[5] Univ North Carolina Chapel Hill, Eshelman Sch Pharm, Chapel Hill, NC USA
[6] Certara, Canterbury, Kent, England
关键词
antibiotics; epithelial lining fluid; lung; pharmacokinetics; prediction; PLASMA; PHARMACOKINETICS;
D O I
10.1007/s11095-017-2336-7
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
引用
收藏
页数:4
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