Toward a Medipix2 coded aperture gamma microscope

被引:0
|
作者
Accorsi, R [1 ]
Autiero, M [1 ]
Celentano, L [1 ]
Laccetti, P [1 ]
Lanza, RC [1 ]
Marotta, M [1 ]
Mettivier, G [1 ]
Montesi, MC [1 ]
Riccio, P [1 ]
Roberti, G [1 ]
Russo, P [1 ]
机构
[1] Childrens Hosp Philadelphia, Dept Radiol, Philadelphia, PA 19104 USA
关键词
D O I
暂无
中图分类号
TL [原子能技术]; O571 [原子核物理学];
学科分类号
0827 ; 082701 ;
摘要
We report on tests of a radionuclide imaging system for in vivo investigations in small animals with low energy gamma-rays as from I-125 (27-35 keV). The system imaging optics features a high resolution coded aperture mask and a fine pitch silicon hybrid pixel detector of the Medipix2 series (55 mu m pitch). The coded aperture (no-two-holes-touching MURA 62x62) had 70 pm holes in 75 pm tungsten, and was used in a 2:1 magnification for a Field of View of about 7 mm. Laboratory tests with a Cd-109 22-keV source and in vivo mouse thyroid imaging tests with I-125 show a system resolution of about 110 mu m. This low energy, semiconductor-based, compact gamma camera is the basic imaging unit of a small animal Single Photon Emission Computed Tomography system with deep sub-millimeter resolution.
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页码:2461 / 2464
页数:4
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