Secoiridoid glucosides with free radical scavenging activity from the leaves of Syringa dilatata

被引：34
|
作者：
Oh, H
Ko, EK
Kim, DH
Jang, KK
Park, SE
Lee, HS
Kim, YC [1 ]
机构：
[1] Wonkwang Univ, Coll Pharm, Iksan 570749, Chonbuk, South Korea
[2] Wonkwang Univ, MRRC, Iksan 570749, Chonbuk, South Korea
[3] Wonkwang Univ, Grad Sch Oriental Med, Iksan, South Korea
[4] Korea Food & Drug Adm, Seoul, South Korea
来源：
PHYTOTHERAPY RESEARCH | 2003年 / 17卷 / 04期
关键词：
Syringa dilatata; free radical scavenger; secoiridoid;
D O I：
10.1002/ptr.1148
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Activity-guided fractionation of the EtOAc and MeOH extract of the leaves of Syringa dilatata NAKAI furnished one free radical scavenger, the secoiridoid glucoside oleuropein together with ligstroside and an iridoid glucoside, syringopicroside. Oleuropein interacted with the stable free radical, 1,1-diphenyl-2-picrylhydrazyl (DPPH), and showed an IC50 value of 40.4 muM. L-Ascorbic acid as a positive control showed an IC50 value of 50.3 muM. Copyright (C) 2003 John Wiley Sons, Ltd.
引用
收藏
页码：417 / 419
页数：3
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