Serum Colorectal Cancer Biomarkers Unraveled by NMR Metabolomics: Past, Present, and Future

被引：10

作者：

Salmeron, Ana M. ^{[1
]}

Tristan, Ana, I ^{[1
]}

Abreu, Ana C. ^{[1
]}

Fernandez, Ignacio ^{[1
]}

机构：

[1] Univ Almeria, Res Ctr CIAIMBITAL, Dept Chem & Phys, Almeria 04120, Spain

来源：

ANALYTICAL CHEMISTRY | 2022年 / 94卷 / 01期

关键词：

MAGNETIC-RESONANCE-SPECTROSCOPY; CLINICAL METABOLOMICS; MULTIVARIATE-ANALYSIS; ANALYTICAL-CHEMISTRY; H-1-NMR SPECTRA; DISCOVERY; IDENTIFY; NORMALIZATION; CHEMOMETRICS; METABOLITES;

D O I：

10.1021/acs.analchem.1c04360

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

colorectal cancer (CRC) is a malignant growth, known as polyp, located on the inner lining of the large intestine, which is constituted by the colon and rectum. Its development begins when cells start growing continuously, modifying their shape, size, and other related characteristics.1 This can lead to cancer over time, and it can be presented in two ways, as adenomatous polyps (adenomas), which are able to turn into cancer, and as inflammatory or hyperplastic polyps, which are more frequent and in general are not precancerous. © 2021 The Authors. Published by American Chemical Society.

引用

页码：417 / 430

页数：14

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