Clinical research methods for treatment, diagnosis, prognosis, etiology, screening, and prevention: A narrative review

被引：32

作者：

Yao, Xiaomei ^{[1
,2
,3
]}

Florez, Ivan D. ^{[3
,4
]}

Zhang, Ping ^{[5
]}

Zhang, Chongfan ^{[2
]}

Zhang, Yi ^{[6
]}

Wang, Chunxue ^{[7
]}

Liu, Xiaofang ^{[8
]}

Nie, Xiuhong ^{[9
]}

Wei, Bing ^{[9
]}

Ghert, Michelle A. ^{[1
,10
]}

机构：

[1] McMaster Univ, Dept Oncol, 711 Concess St, Hamilton, ON L8V 1C3, Canada

[2] Fudan Univ, Childrens Hosp, Ctr Clin Practice Guideline Conduct & Evaluat, Shanghai, Peoples R China

[3] McMaster Univ, Dept Hlth Res Methods Evidence & Impact, Hamilton, ON, Canada

[4] Univ Antioquia, Dept Pediat, Antioquia, Colombia

[5] Fudan Univ, Childrens Hosp, Chinese Journal Evidence Based Pediat, Editorial Off, Shanghai, Peoples R China

[6] Capital Med Univ, Xuanwu Hosp, Div Thorac Surg, Beijing, Peoples R China

[7] Capital Med Univ, Beijing Tiantan Hosp, Div Neuropsychiat & Behav Neurol & Clin Psychol, Beijing, Peoples R China

[8] Capital Med Univ, Tongren Hosp, Div Respirol, Beijing, Peoples R China

[9] Capital Med Univ, Xuanwu Hosp, Div Respirol, Beijing, Peoples R China

[10] McMaster Univ, Juravinski Canc Ctr, Div Orthoped Surg, Hamilton, ON, Canada

来源：

JOURNAL OF EVIDENCE BASED MEDICINE | 2020年 / 13卷 / 02期

关键词：

clinical research methods; diagnosis; literature search; prognosis; treatment; SYSTEMATIC REVIEWS; CONDUCT; BIAS; TOOL; RISK;

D O I：

10.1111/jebm.12384

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This narrative review is an introduction for health professionals on how to conduct and report clinical research on six categories: treatment, diagnosis/differential diagnosis, prognosis, etiology, screening, and prevention. The importance of beginning with an appropriate clinical question and the exploration of how appropriate it is through a literature search are explained. There are three methodological directives that can assist clinicians in conducting their studies from a methodological perspective: (1) how to conduct an original study or a systematic review, (2) how to report an original study or a systematic review, and (3) how to assess the quality or risk of bias for a previous relevant original study or systematic review. This methodological overview article would provide readers with the key points and resources regarding how to perform high-quality research on the six main clinical categories.

引用

页码：130 / 136

页数：7

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