Hair cortisol as a biological marker for burnout symptomatology

被引:47
|
作者
Penz, Marlene [1 ]
Stalder, Tobias [1 ,2 ]
Miller, Robert [1 ,3 ]
Ludwig, Vera M. [1 ]
Kanthak, Magdalena K. [1 ]
Kirschbaum, Clemens [1 ]
机构
[1] Tech Univ Dresden, Dept Biol Psychol, Dresden, Germany
[2] Univ Siegen, Clin Psychol, Sieger, Germany
[3] Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden
关键词
Burnout; Depression; Glucocorticoids; Hair cortisol; Biomarkers; STRESS; PROFILES; HUMANS; AXIS;
D O I
10.1016/j.psyneuen.2017.07.485
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Burnout is a syndrome with negative impact on cognitive performance and mood as a consequence of long-term stress at work. It is further associated with increased risk for mental and physical diseases. One potential pathway to mediate chronic work-stress and adverse health conditions in burnout is through alterations in longterm glucocorticoid secretion. Here, we present cross-sectional data on hair cortisol/cortisone (hairF/hairE) concentrations and burnout from a population-based sample of the Dresden Burnout Study (DBS; N = 314 hair samples). Burnout symptoms (emotional exhaustion, cynical attitudes toward work, and reduced efficacy) were assessed with the Maslach Burnout Inventory-General Survey (MBI-GS). To control for potential confounds, depressivity was as well assessed using the Patient Health Questionnaire (PHQ-9) screening instrument for major depression. The present findings indicate specific hypercortisolism in participants who suffer from burnout. No significant associations were found between depressivity and hairF/hairE.
引用
收藏
页码:218 / 221
页数:4
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