Phase II, open label, multi-dose study of 89-Zr-Df-IAB22M2C (CD8 Immuno-PET Tracer): technical handling and injection instructions for optimal tracer administration

被引：0

作者：

Allred, Kaylee ^{[1
]}

Sanders, Quinten ^{[1
]}

Prince, Monica ^{[1
]}

Korn, Ron ^{[2
]}

Wilson, Ian ^{[2
]}

Le, William ^{[2
]}

Weiss, Avital ^{[2
]}

Abbott, Amanda ^{[3
]}

Hays, David ^{[1
]}

机构：

[1] CARTI Canc Ctr, Little Rock, AR USA

[2] ImaginAb, Inglewood, CA USA

[3] SNMMI, Reston, VA USA

来源：

JOURNAL OF NUCLEAR MEDICINE | 2021年 / 62卷

关键词：

D O I：

暂无

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

3004

引用

页数：2

共 8 条

[1] A phase II, open-label, multi-dose study of [89Zr]Zr-Df-IAB22M2C (CD8 cell PET tracer) PET/CT in patients with selected advanced or metastatic solid malignancies scheduled to receive standard of care immunotherapy, as single agent or in combination
Margolin, K. A.
Korn, R.
Farwell, M.
Postow, M. A.
Hays, D.
Wilson, I. A.
Le, W. H.
ANNALS OF ONCOLOGY, 2021, 32 : S930 - S930
[2] CD8 Positron Emission Tomography (PET/CT) Imaging with 89Zr-Df-IAB22M2C in Patients with Inclusion Body Myositis
Quinn, Colin
Moulton, Kelsey
Korn, Ron
Le, William
Goel, Niti
Farwell, Michael
Greenberg, Steven
ARTHRITIS & RHEUMATOLOGY, 2021, 73 : 1427 - 1429
[3] Use of [89Zr]Zr-Df-IAB22M2C CD8 PET for Directing Solid Tumor Biopsies to Assess the Immune Status Within the Tumor Microenviroment (TME)
Hays, D.
St Amour, E.
Randall, C.
Wilson, I.
Le, W.
Korn, R.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2021, 48 (SUPPL 1) : S229 - S229
[4] First in Human Phase I Imaging Study With 89Zr-IAB22M2C Anti CD8 Minibody in Patients with Solid Tumors
Pandit-Taskar, Neeta
Postow, Micheal
O'Donoghue, Joseph
Harding, James
Ziolkowska, Martha
Lyashchenko, Serge
Lewis, Jason
Wu, Anna
Le, William
Gudas, Jean
Korn, Ronald
Torgov, Michael
Wolchok, Jedd
Weber, Wolfgang
JOURNAL OF NUCLEAR MEDICINE, 2018, 59
[5] Monitoring intratumoral CD8 T cell infiltrates in human stem cell engrafted mice during single agent and combination immunotherapy with T cell bispecific antibodies using the human PET-tracer 89Zr-Df-IAB22M2C
Griessinger, Christoph M.
Mascioni, Alessandro
Jia, Fang
Torgov, Michael
Nayak, Tapan
Mohan, Preethi Latha Bhavani
Nicolini, Valeria G.
Sam, Johannes
Claus, Christina
Ferrara-Koller, Claudia
Bacac, Marina
Umana, Pablo
Wilson, Ian
Klein, Christian
Tessier, Jean J.
CANCER RESEARCH, 2019, 79 (13)
[6] CD8 PET IMAGING OF TUMOR INFILTRATING T CELLS IN ADVANCED SOLID TUMORS: A PHASE I FIRST-INHUMAN STUDY OF 89ZR-IAB22M2C, A RADIOLABELED ANTI-CD8 MINIBODY
Farwell, Michael
Gamache, Raymond
Pandit-Taskar, Neeta
Postow, Mike
Gordon, Michael
Wilson, Ian
Mascioni, Alessandro
Wu, Anna
Le, William
Weiss, Avital
Korn, Ronald
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020, 8 : A179 - A180
[7] The PET-Tracer 89Z -Df-IAB22M2C Enables Monitoring of Intratumoral CD8 T-cell Infiltrates in Tumor-Bearing Humanized Mice after T-cell Bispecific Antibody Treatment
Griessinger, Christoph M.
Olafsen, Tove
Mascioni, Alessandro
Jiang, Ziyue Karen
Zamilpa, Charles
Jia, Fang
Torgov, Michael
Romero, Jason M.
Marchioni, Filippo
Satpayev, Daulet
Lee, Chenyu
Zhang, Green
Nayak, Tapan K.
Pincha, Mudita
Amann, Maria
Mohan, Preethi L. B.
Richard, Marine
Nicolini, Valeria G.
Sam, Johannes
Claus, Christina
Ferrara, Claudia
Brunker, Peter
Bacac, Marina
Umana, Pablo
Ruttinger, Dominik
Wilson, Ian A.
Gudas, Jean
Klein, Christian
Tessier, Jean J. L.
CANCER RESEARCH, 2020, 80 (13) : 2903 - 2913
[8] CD8-Targeted PET Imaging of Tumor-Infiltrating T Cells in Patients with Cancer: A Phase I First-in-Humans Study of 89Zr-Df-IAB22M2C, a Radiolabeled Anti-CD8 Minibody
Farwell, Michael D.
Gamache, Raymond F.
Babazada, Hasan
Hellmann, Matthew D.
Harding, James J.
Korn, Ron
Mascioni, Alessandro
Le, William
Wilson, Ian
Gordon, Michael S.
Wu, Anna M.
Ulaner, Gary A.
Wolchok, Jedd D.
Postow, Michael A.
Pandit-Taskar, Neeta
JOURNAL OF NUCLEAR MEDICINE, 2022, 63 (05) : 720 - 726

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