An alkaloid, two conjugate sesquiterpenes and a phenylpropanoid from Pachypodanthium confine Engl. and Diels

被引:19
|
作者
Mathouet, Hilarion
Elomri, Abdelhakim
Lameiras, Pedro
Daich, Adam
Verite, Philippe
机构
[1] Univ Rouen, Fac Pharm, ADEN EA 3234, Chim Analyt Lab, F-76183 Rouen 1, France
[2] Univ Havre, UFR Sci & Tech, EA3221, URCOM, F-76058 Le Havre, France
[3] Univ Rouen, CNRS, UMR 6014, IRCOF,Lab RMN, F-76821 Mont St Aignan, France
[4] Univ Rouen, Fac Pharm, UMR 6014 CNRS, Lab Pharmacognosie, F-76183 Rouen, France
关键词
Pachypodanthium confine; Annonaceae; phenylpropanoid; conjugate sesquiterpenes; N-acetylpachypodanthine; APORPHINE ALKALOIDS; STAUDTII-ENGL; ET-DIELS; ANNONACEAE;
D O I
10.1016/j.phytochem.2007.04.001
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Two sesquiterpene-trimethoxystyrene conjugates (E)-1-[3'-(4'',8''-dimethylnona-3",7"-dienyl)cyclohex-3'-enyl]-2,4,5-trimethoxybenzene (1) and (Z)-1-[3'-(4",8"-dimethylnona-3",7"-dienyl)cyclohex-3'-enyl]-2,4,5-trimethoxybenzene (2), a phenylpropanoid 1,2,4-trimethoxy-5 -(1-methoxy-ethyl)-benzene (3), and an aporphine alkaloid N-acetylpachypodanthine (4), were isolated in addition to several known compounds from cyclohexane, dichloromethane and alkaloid extracts from bark of Pachypodanthium confine. The structures of these compounds were established based on the interpretation of their high resolution NMR (HSQC, HMBC, COSY and NOESY) spectral data. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1813 / 1818
页数:6
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