Antibiotic resistance

被引：685
|
作者：
Frieri, Marianne [1 ]
Kumar, Krishan [2 ]
Boutin, Anthony [3 ]
机构：
[1] Nassau Univ, Med Ctr, Div Allergy Immunol, Dept Med, 2201 Hempstead Turnpike, E Meadow, NY 11554 USA
[2] Nassau Univ, Med Ctr, Dept Emergency Med, Div Pediat, 2201 Hempstead Turnpike, E Meadow, NY 11554 USA
[3] Nassau Univ, Med Ctr, Dept Emergency Med, Adult Emergency Med, 2201 Hempstead Turnpike, E Meadow, NY 11554 USA
来源：
JOURNAL OF INFECTION AND PUBLIC HEALTH | 2017年 / 10卷 / 04期
关键词：
Antibiotic resistance; Biofilms; Infections; Public health; Emergency Department; STAPHYLOCOCCUS-AUREUS COLONIZATION; BACTERIAL; INFECTION; IMPACT;
D O I：
10.1016/j.jiph.2016.08.007
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Antimicrobial resistance in bacterial pathogens is a challenge that is associated with high morbidity and mortality. Multidrug resistance patterns in Gram-positive and -negative bacteria are difficult to treat and may even be untreatable with conventional antibiotics. There is currently a shortage of effective therapies, lack of successful prevention measures, and only a few new antibiotics, which require development of novel treatment options and alternative antimicrobial therapies. Biofilms are involved in multidrug resistance and can present challenges for infection control. Virulence, Staphylococcus aureus, Clostridium difficile infection, vancomycin-resistant enterococci, and control in the Emergency Department are also discussed. (C) 2016 King Saud Bin Abdulaziz University for Health Sciences. Published by Elsevier Limited. All rights reserved.
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页码：369 / 378
页数：10
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