Recent advancements in hybridized polymer nano-biocomposites for tissue engineering

被引:18
|
作者
Idumah, Christopher Igwe [1 ]
Ezika, Anthony Chidi [2 ,3 ]
机构
[1] Nnamdi Azikiwe Univ, Fac Engn, Dept Polymer & Text Engn, Awka, Anambra State, Nigeria
[2] Tshwane Univ Technol, Fac Engn & Built Environm, Inst NanoEngn Res INER, Pretoria, South Africa
[3] Tshwane Univ Technol, Fac Engn & Built Environm, Dept Chem Met & Mat Engn, Pretoria, South Africa
关键词
Bioactive glass; biomedical applications; nanoparticles; polymer nanocomposites; EXFOLIATED GRAPHENE NANOPLATELETS; MESENCHYMAL STEM-CELLS; COMPOSITE SCAFFOLDS; EMERGING TRENDS; ELECTROSPUN NANOFIBERS; FLAME RETARDANCY; BIOACTIVE GLASS; BONE; CHITOSAN; NANOMATERIALS;
D O I
10.1080/00914037.2021.1960344
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Emerging novel approaches for bone tissue regeneration and engineering are based on bioactive materials scaffolding architectures for mimicking naturally occurring extracellular matrix while also acting as structural platform for cells attachment, multiplication, migration as well as functionalization. Polymeric nano-biocomposites formed from organic/inorganic hybrid biomaterials constructed from comingling of biodegradable polymeric matrices and bioactive inorganic substrates have recently garnered great attention as a result of prevalent efficient performances. Therefore, this paper expounds on state of the art recently emerging trends in bioactive, as well as biodegradable nanocomposites, along with organic/inorganic hybridized biomaterials, in addition to inherent usage for tissue engineering as well as bone regeneration. Emphases are given to nanocomposites oriented on bioactive glasses (BGs) and nanoparticulate hydroxyapatite (nHA)/polymeric matrices (PMs) along with their hybridized components.
引用
收藏
页码:1262 / 1276
页数:15
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