Fluoxetine treatment of children with selective mutism: An open trial

被引：99

作者：

Dummit, SE ^{[1
]}

Klein, RG ^{[1
]}

Tancer, NK ^{[1
]}

Asche, B ^{[1
]}

Martin, J ^{[1
]}

机构：

[1] COLUMBIA UNIV, COLL PHYS & SURG, NEW YORK STATE PSYCHIAT INST, NEW YORK, NY USA

来源：

JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY | 1996年 / 35卷 / 05期

关键词：

elective mutism; selective mutism; anxiety; social phobia; avoidant disorder; child; adolescent; fluoxetine;

D O I：

10.1097/00004583-199605000-00016

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

Objective: A pilot study was designed to evaluate the safety and efficacy of fluoxetine treatment for children with selective mutism (elective mutism in DSM-III-R). Method: Twenty-one children (mean age 8.2 years, range 5 through 14) participated in a 9-week open trial of fluoxetine in graduated doses (mean end dose 28.1 mg, range 10 to 60 mg) with systematic baseline and outcome evaluations and weekly clinical assessment. Results: All 21 children met DSM-III-R and DSM-IV criteria for anxiety disorders. After fluoxetine treatment, 76% were improved, with diminished anxiety and increased speech in public settings, including school. Improvement at week 9 was inversely correlated with age. Conclusions: Persistent selective mutism presenting with comorbid anxiety disorders may respond to fluoxetine treatment.

引用

页码：615 / 621

页数：7

共 50 条

[1] Fluoxetine treatment of selective mutism in pervasive developmental disorder
Silveira, R
Jainer, AK
Bates, G
[J]. INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE, 2004, 8 (03) : 179 - 180
[2] Selective mutism in children: Understanding and treatment
Oerbeck, Beate
Kristensen, Hanne
Eskeland, Benedicte
Mc Nicholas, Fiona
[J]. EUROPEAN CHILD & ADOLESCENT PSYCHIATRY, 2011, 20 (01) : S16 - S16
[3] Treatment of postoperative cerebellar mutism with fluoxetine
Ali Akhaddar
Mohcine Salami
Abad Cherif El Asri
Mohamed Boucetta
[J]. Child's Nervous System, 2012, 28 : 507 - 508
[4] Treatment of postoperative cerebellar mutism with fluoxetine
Akhaddar, Ali
Salami, Mohcine
El Asri, Abad Cherif
Boucetta, Mohamed
[J]. CHILDS NERVOUS SYSTEM, 2012, 28 (04) : 507 - 508
[5] Effectiveness of a behavioral treatment protocol for selective mutism in children: Design of a randomized controlled trial
Pereira, C. Rodrigues
Ensink, Judith B. M.
Guldner, Max G.
Kan, Kees J.
de Jonge, Maretha, V
Lindauer, Ramon J. L.
Utens, Elisabeth M. W. J.
[J]. CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS, 2020, 19
[6] AN OPEN TRIAL OF FLUOXETINE IN THE TREATMENT OF PANIC ATTACKS
GORMAN, JM
LIEBOWITZ, MR
FYER, AJ
GOETZ, D
CAMPEAS, RB
FYER, MR
DAVIES, SO
KLEIN, DF
[J]. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 1987, 7 (05) : 329 - 332
[7] Fluoxetine in the treatment of anger: An open clinical trial
Rubey, RN
Johnson, MR
Emmanuel, N
Lydiard, RB
[J]. JOURNAL OF CLINICAL PSYCHIATRY, 1996, 57 (09) : 398 - 401
[8] Phenelzine treatment of selective mutism in four prepubertal children
Golwyn, DH
Sevlie, CP
[J]. JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 1999, 9 (02) : 109 - 113
[9] Treatment for Children With Selective Mutism: An Integrative Behavioral Approach
Paul, Howard A.
[J]. CHILD & FAMILY BEHAVIOR THERAPY, 2013, 35 (04) : 337 - 341
[10] CASE-STUDY - FLUOXETINE IN THE MULTIMODAL TREATMENT OF A PRESCHOOL-CHILD WITH SELECTIVE MUTISM
WRIGHT, HH
CUCCARO, ML
LEONHARDT, TV
KENDALL, DF
ANDERSON, JH
[J]. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 1995, 34 (07): : 857 - 862

← 1 2 3 4 5 →