Intermolecular iodofunctionalization of allenamides with indoles, pyrroles, and furans: synthesis of iodine-substituted Z-enamides

被引：27

作者：

Li, Honghe ^{[1
]}

Li, Xiaoxiao ^{[1
]}

Zhao, Zhigang ^{[1
]}

Ma, Ting ^{[1
]}

Sun, Chenyang ^{[1
]}

Yang, Bowen ^{[1
]}

机构：

[1] Southwest Univ Nationalities, Coll Chem & Environm Protect Engn, Chengdu 610041, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 66期

关键词：

N-ALLENYL AMIDES; ELECTROPHILIC ACTIVATION; MEDIATED CYCLIZATION; GOLD; CYCLOADDITION; ACID; IODOCYCLIZATION; DEAROMATIZATION; CHEMISTRY; ALKENES;

D O I：

10.1039/c6cc05046h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new method was developed to synthesize iodine-substituted Z-enamides through N-iodosuccinimide-mediated intermolecular iodofunctionalization of allenamides with indoles, pyrroles, and furans. These reactions proceed rapidly and tolerate a broad scope of substrates. The conjugated sulfimide ion species probably acts as the key intermediate.

引用

页码：10167 / 10170

页数：4