Can maternal-child microbial seeding interventions improve the health of infants delivered by Cesarean section?

被引：23
|
作者：
Hourigan, Suchitra K. [1 ]
Dominguez-Bello, Maria Gloria [2 ]
Mueller, Noel T. [3 ]
机构：
[1] NIAID, Clin Microbiome Unit CMU, Lab Host Immun & Microbiome, NIH, 9000 Rockville Pike, Bethesda, MD 20892 USA
[2] Rutgers State Univ, Dept Biochem & Microbiol, New Brunswick, NJ 08854 USA
[3] Johns Hopkins Univ, Dept Epidemiol, Bloomberg Sch Publ Hlth, Baltimore, MD 21218 USA
来源：
CELL HOST & MICROBE | 2022年 / 30卷 / 05期
基金：
美国国家卫生研究院;
关键词：
BORN INFANTS; MULTIPLE; SHAPES;
D O I：
10.1016/j.chom.2022.02.014
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Maternal-child microbial seeding interventions expose Cesarean-section (C-section)-delivered infants to the maternal microbiome they bypass during Cesarean delivery. It is theorized such interventions restore the microbiome and normalize immune development to reduce the occurrence of C-section-associated inflammatory conditions. Here we discuss the rationale, evidence, and controversies surrounding such interventions.
引用
收藏
页码：607 / 611
页数：5
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