Nickel-catalyzed α-alkylation of ketones with benzyl alcohols

被引：10
|
作者：
Wu, Di [1 ]
Wang, Yubin [1 ]
Li, Min [1 ]
Shi, Lei [1 ]
Liu, Jichang [1 ,2 ]
Liu, Ning [1 ]
机构：
[1] Shihezi Univ, Sch Chem & Chem Engn, Key Lab Green Proc Chem Engn Xinjiang Bingtuan, North 4th Rd, Shihezi 832003, Xinjiang, Peoples R China
[2] East China Univ Sci & Technol, Sch Chem Engn, Shanghai, Peoples R China
来源：
APPLIED ORGANOMETALLIC CHEMISTRY | 2022年 / 36卷 / 02期
基金：
中国国家自然科学基金;
关键词：
alkylation; coupling reaction; N-heterocyclic carbenes; nickel catalysis; COMPLEXES; GENERATION; CONVERSION; CARBENES;
D O I：
10.1002/aoc.6493
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
We reported an efficient method for alpha-alkylation of ketones with benzyl alcohols using the pyridine-bridged pincer-type N-heterocyclic carbenes nickel complexes as catalysts. A wide range of ketones and benzyl alcohols were efficiently converted into various alkylated products in moderate to high yields. In addition, these nickel complexes were also successfully applied for the synthesis of a wide range of quinoline derivatives.
引用
收藏
页数：10
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