Design, synthesis, and biological activity of hydroxyindoles as non-ATP competitive pp60c-src tyrosine kinase inhibitors.

被引:0
|
作者
Milkiewicz, KL
Marsilje, TH
Woodworth, RP
Bifulco, N
Hangauer, M
Hangauer, DG
机构
[1] SUNY Buffalo, Dept Med Chem, Buffalo, NY 14260 USA
[2] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA
[3] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
51-MEDI
引用
收藏
页码:U545 / U545
页数:1
相关论文
共 50 条
  • [1] The design, synthesis and activity of non-ATP competitive inhibitors of pp60c-src tyrosine kinase.: Part 2:: Hydroxyindole derivatives
    Milkiewicz, KL
    Marsilje, TH
    Woodworth, RP
    Bifulco, N
    Hangauer, MJ
    Hangauer, DG
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2000, 10 (05) : 483 - 486
  • [2] The design, synthesis and activity of non-ATP competitive inhibitors of pp60c-src tyrosine kinase.: Part 1:: Hydroxynaphthalene derivatives
    Marsilje, TH
    Milkiewicz, KL
    Hangauer, DG
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2000, 10 (05) : 477 - 481
  • [3] Novel Aminomethylindole Derivatives as Inhibitors of pp60c-Src Tyrosine Kinase: Synthesis and Biological Activity
    Isgor, Yasemin G.
    Kilic, Zuhal
    Olgen, Sureyya
    CHEMICAL BIOLOGY & DRUG DESIGN, 2008, 72 (06) : 599 - 604
  • [4] De novo design of inhibitors of protein tyrosine kinase pp60c-src
    Langer, T
    König, MA
    Schischkow, G
    Guccione, S
    MOLECULAR MODELING AND PREDICTION OF BIOACTIVITY, 2000, : 361 - 362
  • [5] Structural basis for the activity of pp60c-src protein tyrosine kinase inhibitors
    Prabhu, NV
    Siddiqui, SA
    McMurray, JS
    Pettitt, BM
    BIOPOLYMERS, 2001, 59 (03) : 167 - 179
  • [6] PHOSPHATASE-ACTIVITY OF PP60C-SRC TYROSINE KINASE
    BOERNER, RJ
    KASSEL, D
    WEIGL, D
    GAMPE, R
    CONSLER, T
    WILLARD, D
    DELACY, P
    ELLIS, B
    LUTHER, M
    RODRIGUEZ, M
    KNIGHT, WB
    FASEB JOURNAL, 1994, 8 (07): : A1231 - A1231
  • [7] CORRELATION OF THE PHOSPHORYLATION STATES OF PP60C-SRC WITH TYROSINE KINASE-ACTIVITY
    BARKER, SC
    BOERNER, RJ
    KASSEL, D
    KNIGHT, WB
    FASEB JOURNAL, 1995, 9 (06): : A1305 - A1305
  • [8] Evaluation of New Indole and Bromoindole Derivatives as pp60c-Src Tyrosine Kinase Inhibitors
    Kilic, Zuehal
    Isgor, Yasemin G.
    Olgen, Sureyya
    CHEMICAL BIOLOGY & DRUG DESIGN, 2009, 74 (04) : 397 - 404
  • [9] PP60C-SRC KINASE-ACTIVITY IN BOVINE CORONARY EXTRACTS IS STIMULATED BY ATP
    DISALVO, J
    GIFFORD, D
    KOKKINAKIS, A
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1988, 153 (01) : 388 - 394
  • [10] PP60C-SRC KINASE-ACTIVITY IN CORONARY ARTERIAL EXTRACTS IS STIMULATED BY ATP
    DISALVO, J
    GIFFORD, D
    KOKKINAKIS, A
    FASEB JOURNAL, 1988, 2 (06): : A1757 - A1757