Hematopoietic stem cell transplantation in adults with acute myeloid leukemia

被引:33
|
作者
Hamadani, Mehdi [2 ]
Awan, Farrukh T. [2 ]
Copelan, Edward A. [1 ]
机构
[1] Cleveland Clin Fdn, Taussig Canc Ctr, Dept Hematol Oncol & Blood Disorders, Cleveland, OH 44195 USA
[2] Ohio State Univ, Arthur G James Canc Hosp, Columbus, OH USA
关键词
acute myeloid leukemia; hematopoietic stem cell transplantation; bone marrow transplantation; reduced intensity; acute leukemia; graft-versus-leukemia effect;
D O I
10.1016/j.bbmt.2008.02.019
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hematopoietic stem cell transplantation (HSCT) is an integral part of the treatment of many patients with acute myeloid leukemia (AML). Despite extensive study, the appropriate role and timing of allogeneic and autologous transplantation in AML are poorly defined. This review critically analyzes the extensive literature, focusing on the recent advances, and provides practical recommendations for the use of HSCT in AML. (C) 2008 American Society for Blood and Marrow Transplantation.
引用
收藏
页码:556 / 567
页数:12
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