Polyvalent Nucleic Acid/Mesoporous Silica Nanoparticle Conjugates: Dual Stimuli-Responsive Vehicles for Intracellular Drug Delivery

被引：271

作者：

Chen, Cuie ^{[1
,2
,3
]}

Geng, Jie ^{[1
,2
,3
]}

Pu, Fang ^{[1
,2
,3
]}

Yang, Xinjian ^{[1
,2
,3
]}

Ren, Jinsong ^{[1
,2
,3
]}

Qu, Xiaogang ^{[1
,2
,3
]}

机构：

[1] Chinese Acad Sci, State Key Lab Rare Earth Resources Utilizat, Changchun Inst Appl Chem, Changchun 130022, Peoples R China

[2] Chinese Acad Sci, Biol Chem Lab, Changchun Inst Appl Chem, Changchun 130022, Peoples R China

[3] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 04期

基金：

中国国家自然科学基金;

关键词：

click chemistry; DNA; drug delivery; mesoporous materials; nanoparticles; MESOPOROUS SILICA; CONTROLLED-RELEASE; GUEST MOLECULES; CLICK CHEMISTRY; GOLD NANOPARTICLES; CANCER-CELLS; NANOVALVES; DNA; SYSTEM; FUNCTIONALIZATION;

D O I：

10.1002/anie.201005471

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Blocked tubes: Attachment of self-complementary duplex DNA to the openings of mesoporous silica nanoparticles results in a cap for trapping guest molecules. The cargo can be released either by thermal stimuli or by the introduction of DNase I, both of which open the capping DNA structure (see picture). © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：882 / 886

页数：5

共 50 条

[1] Ammonium salt modified mesoporous silica nanoparticles for dual intracellular stimuli-responsive gene delivery
Li, Yujie
Hei, Mingyang
Xu, Yufang
Qian, Xuhong
Zhu, Weiping
[J]. JOURNAL OF CONTROLLED RELEASE, 2017, 259 : E139 - E140
[2] Stimuli-responsive nucleic acid nanostructures for efficient drug delivery
Yang, Changping
Wu, Xiaohui
Liu, Jianbing
Ding, Baoquan
[J]. NANOSCALE, 2022, 14 (48) : 17862 - 17870
[3] Advances in mesoporous silica nanoparticles for targeted stimuli-responsive drug delivery
Baeza, Alejandro
Colilla, Montserrat
Vallet-Regi, Maria
[J]. EXPERT OPINION ON DRUG DELIVERY, 2015, 12 (02) : 319 - 337
[4] Capped mesoporous silica nanoparticles as stimuli-responsive controlled release systems for intracellular drug/gene delivery
Zhao, Yannan
Vivero-Escoto, Juan L.
Slowing, Igor I.
Trewyn, Brian C.
Lin, Victor S-Y
[J]. EXPERT OPINION ON DRUG DELIVERY, 2010, 7 (09) : 1013 - 1029
[5] Stimuli-Responsive Silica Silanol Conjugates: Strategic Nanoarchitectonics in Targeted Drug Delivery
Mohanan, Shan
Guan, Xinwei
Liang, Mingtao
Karakoti, Ajay
Vinu, Ajayan
[J]. SMALL, 2024, 20 (39)
[6] Targeted and stimuli-responsive mesoporous silica nanoparticles for drug delivery and theranostic use
Aquib, Md
Farooq, Muhammad A.
Banerjee, Parikshit
Akhtar, Fahad
Filli, Mensura S.
Boakye-Yiadom, Kofi O.
Kesse, Samuel
Raza, Faisal
Maviah, Mily B. J.
Mavlyanova, Rukhshona
Wang, Bo
[J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2019, 107 (12) : 2643 - 2666
[7] Advances in mesoporous silica nanoparticles for targeted stimuli-responsive drug delivery: an update
Castillo, Rafael R.
Lozano, Daniel
Gonzalez, Blanca
Manzano, Miguel
Izquierdo-Barba, Isabel
Vallet-Regi, Maria
[J]. EXPERT OPINION ON DRUG DELIVERY, 2019, 16 (04) : 415 - 439
[8] Stimuli-responsive PGMA-gated mesoporous silica for controlled drug delivery
Sun, Yu-Long
Yang, Ying-Wei
[J]. JOURNAL OF CONTROLLED RELEASE, 2013, 172 (01) : E89 - E89
[9] Dual stimuli-responsive nano-vehicles for controlled drug delivery: mesoporous silica nanoparticles end-capped with natural chitosan
Hakeem, Abdul
Duan, Ruixue
Zahid, Fouzia
Dong, Chao
Wang, Boya
Hong, Fan
Ou, Xiaowen
Jia, Yongmei
Lou, Xiaoding
Xia, Fan
[J]. CHEMICAL COMMUNICATIONS, 2014, 50 (87) : 13268 - 13271
[10] Stimuli-responsive delivery vehicles based on mesoporous silica nanoparticles: recent advances and challenges
Zhu, Jianhua
Niu, Yimin
Li, Yang
Gong, Yaxiang
Shi, Huihui
Huo, Qiang
Liu, Yang
Xu, Qunwei
[J]. JOURNAL OF MATERIALS CHEMISTRY B, 2017, 5 (07) : 1339 - 1352

← 1 2 3 4 5 →