PANDAS: pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections - an uncommon, but important indication for tonsillectomy

被引：27

作者：

Heubi, C ^{[1
]}

Shott, SR ^{[1
]}

机构：

[1] Childrens Hosp, Med Ctr, Dept Pediat Otolaryngol, Cincinnati, OH 45229 USA

来源：

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY | 2003年 / 67卷 / 08期

关键词：

PANDAS; obsessive compulsive disorder; Tourette syndrome; tonsillectomy;

D O I：

10.1016/S0165-5876(03)00158-7

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections, also know as "PANDAS," is well described in the neurologic and psychiatric literature. PANDAS is associated with obsessive compulsive disorders (OCD) and tic disorders. The streptococcal infections may trigger an autoimmune reaction that exacerbates these conditions. Recurrent streptococcal tonsillitis is one of the recurrent infections associated with PANDAS. This paper reviews the case reports of two brothers, one with OCD and the other with a tic disorder, both of whom improved significantly after undergoing adenotonsillectomy for treatment of their recurrent tonsillitis. A review of the pathophysiology and current understanding of PANDAS is presented. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：837 / 840

页数：4

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