Genetic variants of Orientia tsutsugamushi identified from scrub typhus cases in Malaysia

被引:0
|
作者
Anis, Mohamed Zan Hafizatul [1 ]
Sasheela, Ponnampalavanar [2 ]
Faridah, Syed Omar Sharifah [2 ]
Savithiri, Puthucheary D. [1 ]
Lim, Yvonne A. L. [3 ]
Tay, Sun Tee [1 ]
机构
[1] Univ Malaya, Fac Med, Dept Med Microbiol, Kuala Lumpur 50603, Malaysia
[2] Univ Malaya, Fac Med, Dept Med, Kuala Lumpur 50603, Malaysia
[3] Univ Malaya, Fac Med, Dept Parasitol, Kuala Lumpur 50603, Malaysia
关键词
RICKETTSIA-TSUTSUGAMUSHI; ANTIGEN GENE; ILLNESS; STRAINS; TAIWAN;
D O I
暂无
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
We report herein the clinical presentation and diagnosis of scrub typhus in three patients attending a teaching hospital in Malaysia. Three genetic variants belonged to the Karp and Gilliam strains of O. tsutsugamushi were amplified from the acute blood samples of the patients by a nested polymerase chain reaction assay. The circulation of different genetic variants of O. tsutsugamushi strains might complicate the presentation and severity of scrub typhus. Loop-PCR is a promising diagnostic tool for rapid diagnosis of scrub typhus.
引用
收藏
页码:203 / 208
页数:6
相关论文
共 50 条
  • [1] Molecular detection of Orientia tsutsugamushi from suspected scrub typhus cases
    Srinivasan, Seethalakshmi
    Menon, Thangam
    [J]. INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY, 2017, 60 (01) : 70 - 73
  • [2] The genotypes of Orientia tsutsugamushi, identified in scrub typhus patients in northern Vietnam
    Nguyen, Hang L. K.
    Pham, Hang T. T.
    Nguyen, Tinh V.
    Hoang, Phuong V. M.
    Le, Mai T. Q.
    Takemura, Taichiro
    Hasebe, Futoshi
    Hayasaka, Daisuke
    Yamada, Akio
    Hotta, Kozue
    [J]. TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2017, 111 (03) : 137 - 139
  • [3] A serosurvey of Orientia tsutsugamushi from patients with scrub typhus
    Kim, D. M.
    Lee, Y. -M.
    Back, J. -H.
    Yang, T. Y.
    Lee, J. H.
    Song, H. -J.
    Shim, S. -K.
    Hwang, K. -J.
    Park, M. -Y.
    [J]. CLINICAL MICROBIOLOGY AND INFECTION, 2010, 16 (05) : 447 - 451
  • [4] Orientia tsutsugamushi in eschars from scrub typhus patients
    Liu, Yun-Xi
    Cao, Wu-Chun
    Gao, Yuan
    Zhang, Jing-Lan
    Yang, Zhan-Qing
    Zhao, Zhong-Tang
    Foley, Janet E.
    [J]. EMERGING INFECTIOUS DISEASES, 2006, 12 (07) : 1109 - 1112
  • [5] Scrub Typhus: The Geographic Distribution of Phenotypic and Genotypic Variants of Orientia tsutsugamushi
    Kelly, Daryl J.
    Fuerst, Paul A.
    Ching, Wei-Mei
    Richards, Allen L.
    [J]. CLINICAL INFECTIOUS DISEASES, 2009, 48 : S203 - S230
  • [6] Dissemination of Orientia tsutsugamushi in a Case of Scrub Typhus
    Han, Yeon-Hee
    Hwang, Joo-Hee
    Lee, Chang-Seop
    [J]. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2019, 100 (02): : 235 - 236
  • [7] Identification of the target cells of Orientia tsutsugamushi in human cases of scrub typhus
    Moron, CG
    Popov, VL
    Feng, HM
    Wear, D
    Walker, DH
    [J]. MODERN PATHOLOGY, 2001, 14 (08) : 752 - 759
  • [8] New Orientia tsutsugamushi strain from scrub typhus in Australia
    Odorico, DM
    Graves, SR
    Currie, B
    Catmull, J
    Nack, Z
    Ellis, S
    Wang, L
    Miller, DJ
    [J]. EMERGING INFECTIOUS DISEASES, 1998, 4 (04) : 641 - 644
  • [9] Genotyping of Orientia tsutsugamushi from humans with scrub typhus, Laos
    Parola, Philippe
    Blacksell, Stuart D.
    Phetsouvanh, Rattanaphone
    Phongmany, Simaly
    Rolain, Jean-Marc
    Day, Nicholas P. J.
    Newton, Paul N.
    Raoult, Didier
    [J]. EMERGING INFECTIOUS DISEASES, 2008, 14 (09) : 1483 - 1485
  • [10] Scrub typhus and antibiotic-resistant Orientia tsutsugamushi
    Lu, Chin-Te
    Wang, Lih-Shinn
    Hsueh, Po-Ren
    [J]. EXPERT REVIEW OF ANTI-INFECTIVE THERAPY, 2021, 19 (12) : 1519 - 1527