Synthesis of 5,11-dialkyl-5,6,11,12-tetrahydro-6,12-epoxydibenzo[b,f][1,5]diazocines from 2-alkylaminobenzaldehydes

被引：0
|
作者：
Ivanov, Dmitry S. [1 ]
Zaitseva, Elvira R. [1 ]
Smirnov, Alexander Yu [1 ,2 ]
Baleeva, Nadezhda S. [1 ,2 ]
Baranov, Mikhail S. [1 ,2 ]
机构：
[1] Russian Acad Sci, Shemyakin Ovchinnikov Inst Bioorgan Chem, 16-10 Miklukho Maklaya St,GSP 7, Moscow 117997, Russia
[2] Pirogov Russian Natl Res Med Univ, Minist Hlth & Social Dev Russian Federat, 1 Ostrovityanova St, Moscow 117997, Russia
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2022年 / 58卷 / 6-7期
基金：
俄罗斯科学基金会;
关键词：
2-alkylaminobenzaldehydes; tetrahydrodiazocines; Troger's base; acidic catalysis; TROGERS BASE; BINDING;
D O I：
10.1007/s10593-022-03097-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple methodology was developed for the synthesis of 5,11-dialkyl-5,6,11,12-tetrahydro-6,12-epoxydibenzo[b,f][1,5]diazocines by treatment of the respective 2-alkylaminobenzaldehydes with hydrogen chloride solution in dioxane at room temperature.
引用
收藏
页码：354 / 357
页数：4
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