Melatonin makes me feel awake!: Seven years of lab experience (2000-2007)

被引：0

作者：

Pelaez, Teresa ^{[1
]}

Mediero, Aranzazu ^{[1
]}

Alarma-Estrany, Pilar ^{[1
]}

Loma, Patricia ^{[1
]}

Guzman-Aranguez, Ana I. ^{[1
]}

Crooke, Almudena ^{[1
]}

Kolligris, Basilio ^{[1
]}

Peral, Assumpta ^{[1
]}

Pintor, Jesus ^{[1
]}

机构：

[1] Univ Complutense Madrid, Dept Bioquim, EU Opt, Madrid 28037, Spain

来源：

ANALES DE LA REAL ACADEMIA NACIONAL DE FARMACIA | 2007年 / 73卷 / 04期

关键词：

melatonin; melatonin receptors; intraocular pressure; MT3; receptor;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The research on the effect of melatonin on intraocular pressure (IOP) is reviewed from the hystorical point of view of our laboratory. The original idea of melatonin modulating intraocular pressure has been improved by using selective compounds for MT2 and specially melatonin MT3 receptors. The selective compound 5-methoxyamino N-acetyltryptamine (5-MCA-NAT) has been an attractive compound due to its ability to reduce IOP about 40%, therefore being a good candidate to the treatment of the ocular hypertension linked to glaucoma. More compounds have been developed and tested permitting us to have a more accurate panorama of those receptors controlling the relevant process of intraocular pressure.

引用

页码：947 / 962

页数：16

共 19 条

[1] Chronic renal failure during seven years period (2000-2007) at tertiary referal center
Paripovic, A.
Stajic, N.
Putnik, J.
Bogdanovic, R.
[J]. PEDIATRIC NEPHROLOGY, 2008, 23 (09) : 1615 - 1615
[2] Mortality trends from diabetes mellitus in the seven socioeconomic regions of Mexico, 2000-2007
Jesus Sanchez-Barriga, Juan
[J]. REVISTA PANAMERICANA DE SALUD PUBLICA-PAN AMERICAN JOURNAL OF PUBLIC HEALTH, 2010, 28 (05): : 368 - 375
[3] North American Energy, 2000-2007: What a Difference Those Years Make!
Dukert, Joseph M.
[J]. AMERICAN REVIEW OF CANADIAN STUDIES, 2007, 37 (01) : 57 - 76
[4] Patient Care Costs in the State Training and Research Hospitals in Istanbul in Years 2000-2007
Aydin, Nursen
Bakoglu, Refika
[J]. PROCEEDINGS OF 7TH INTERNATIONAL STRATEGIC MANAGEMENT CONFERENCE, 2011, 24
[5] Patterns of Psychotropic Drug Use in Pregnancy and Lactation: The Mother Safe Experience 2000-2007
Eamus, M.
Oei, J.
Hill, M.
Taylor, T.
Kennedy, D.
[J]. BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY, 2010, 88 (05) : 362 - 362
[6] 'It Makes Me Feel Old': Understanding the Experience of Recovery From Ankle Fracture at 6 Months in People Aged 50 Years and Over
Tutton, Elizabeth
Gould, Jenny
Lamb, Sarah E. E.
Costa, Matthew L. L.
Keene, David J. J.
[J]. QUALITATIVE HEALTH RESEARCH, 2023, 33 (04) : 308 - 320
[7] CLINICO HEMATOLOGICAL CHARACTERISTICS AND TREATMENT OF 150 NEW MDS PATIENTS. SINGLE CENTER EXPERIENCE DURING 7 YEARS (2000-2007)
Ionita, I.
Cheveresan, M.
Ionita, C.
Cheveresan, L.
Calamar, D.
Ionita, H.
[J]. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2009, 94 : 536 - 536
[8] Health profile of the province of Cordoba. Development and effectiveness of health policies. Years 2000-2007
Peranovich, Andres C.
[J]. REVISTA DE SALUD PUBLICA-CORDOBA, 2012, 16 (03): : 42 - 55
[9] Occupational Injuries to Oregon Workers 24 years and Younger: An Analysis of Workers' Compensation Claims, 2000-2007
Walters, Jaime K.
Christensen, Kari A.
Green, Mandy K.
Karam, Lauren E.
Kincl, Laurel D.
[J]. AMERICAN JOURNAL OF INDUSTRIAL MEDICINE, 2010, 53 (10) : 984 - 994
[10] Mental Health and Substance Use Disorder Spending in the Department of Veterans Affairs, Fiscal Years 2000-2007
Wagner, Todd H.
Sinnott, Patricia
Siroka, Andrew M.
[J]. PSYCHIATRIC SERVICES, 2011, 62 (04) : 389 - 395

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