IGF1R/FAK crosstalk is essential for epithelial-to-mesenchymal transition (EMT), migration, and invasion of TNBC cells

被引：0
|
作者：
Taliaferro-Smith, LaTonia D. [1 ]
Oberlick, Elaine [2 ]
Liu, Tongrui [1 ]
McGlothen, Tanisha Z. [1 ]
O'Regan, Ruth [1 ]
机构：
[1] Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USA
[2] Harvard Univ, Sch Med, Cambridge, MA 02138 USA
来源：
CANCER RESEARCH | 2015年 / 75卷
关键词：
D O I：
10.1158/1538-7445.SABCS14-P2-07-02
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
P2-07-02
引用
收藏
页数：2
相关论文
共 50 条
  • [1] MECHANISM OF IGF INDUCED EPITHELIAL-TO-MESENCHYMAL TRANSITION (EMT) IN MELANOMA PROGRESSION
    Prithviraj, Prashanth
    Jayachandran, Aparna
    Anaka, Matthew
    Cebon, Jonathon
    [J]. ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2012, 8 : 304 - 304
  • [2] FAK activation is required for IGF1R-mediated regulation of EMT, migration, and invasion in mesenchymal triple negative breast cancer cells
    Taliaferro-Smith, LaTonia
    Oberlick, Elaine
    Liu, Tongrui
    McGlothen, Tanisha
    Alcaide, Tiffanie
    Tobin, Rachel
    Donnelly, Siobhan
    Commander, Rachel
    Kline, Erik
    Nagaraju, Ganji Purnachandra
    Havel, Lauren
    Marcus, Adam
    Nahta, Rita
    O'Regan, Ruth
    [J]. ONCOTARGET, 2015, 6 (07) : 4757 - 4772
  • [3] IGF-1R/epithelial-to-mesenchymal transition (EMT) crosstalk suppresses the erlotinib-sensitizing effect of EGFR exon 19 deletion mutations
    Alejandro Vazquez-Martin
    Sílvia Cufí
    Cristina Oliveras-Ferraros
    Violeta Zenobia Torres-Garcia
    Bruna Corominas-Faja
    Elisabet Cuyàs
    Rosa Bonavia
    Joana Visa
    Begoña Martin-Castillo
    Enrique Barrajón-Catalán
    Vicente Micol
    Joaquim Bosch-Barrera
    Javier A. Menendez
    [J]. Scientific Reports, 3
  • [4] IGF-1R/epithelial-to-mesenchymal transition (EMT) crosstalk suppresses the erlotinib-sensitizing effect of EGFR exon 19 deletion mutations
    Vazquez-Martin, Alejandro
    Cufi, Silvia
    Oliveras-Ferraros, Cristina
    Zenobia Torres-Garcia, Violeta
    Corominas-Faja, Bruna
    Cuyas, Elisabet
    Bonavia, Rosa
    Visa, Joana
    Martin-Castillo, Begona
    Barrajon-Catalan, Enrique
    Micol, Vicente
    Bosch-Barrera, Joaquim
    Menendez, Javier A.
    [J]. SCIENTIFIC REPORTS, 2013, 3
  • [5] VEGF mediates epithelial-to-mesenchymal transition (EMT) in HNSCC cells
    Tong, Meng
    Lloyd, Brandon
    Pei, Ping
    Mallery, Susan
    [J]. CANCER RESEARCH, 2009, 69
  • [6] Bmi-1 regulates epithelial-to-mesenchymal transition to promote migration and invasion of breast cancer cells
    Li, Haiyu
    Song, Fangzhou
    Chen, Xingfeng
    Li, Yun
    Fan, Jianjun
    Wu, Xiangmei
    [J]. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2014, 7 (06): : 3057 - 3064
  • [7] ETS1 regulates epithelial-to-mesenchymal transition (EMT) in prostate cancer cells
    Rodgers, Jamie J.
    Epis, Michael
    Cohen, Ronald
    Leedman, Peter
    Harvey, Jennet
    Thomas, Marc
    Bentel, Jacqueline
    [J]. CANCER RESEARCH, 2014, 74 (19)
  • [8] Inhibition of epithelial-to-mesenchymal transition (EMT) in MDCK cells by cyclic AMP
    Romano, Silvia
    Murray, Fiona
    Insel, Paul A.
    [J]. FASEB JOURNAL, 2011, 25
  • [9] Solamargine inhibits the migration and invasion of HepG2 cells by blocking epithelial-to-mesenchymal transition
    Xie, Xiaodong
    Zhu, Haitao
    Zhang, Jia
    Wang, Meiqin
    Zhu, Li
    Guo, Zhen
    Shen, Wenrong
    Wang, Dongqing
    [J]. ONCOLOGY LETTERS, 2017, 14 (01) : 447 - 452
  • [10] Ampelopsin reduces the migration and invasion of ovarian cancer cells via inhibition of epithelial-to-mesenchymal transition
    Liu, Tianfeng
    Liu, Peishu
    Ding, Feng
    Yu, Nina
    Li, Shihong
    Wang, Surong
    Zhang, Xiaofei
    Sun, Xiangxiu
    Chen, Ying
    Wang, Feng
    Zhao, Yunhe
    Li, Bo
    [J]. ONCOLOGY REPORTS, 2015, 33 (02) : 861 - 867
12345