Role of Vitamin D in Rheumatoid Arthritis

被引：24

作者：

Bellan, Mattia ^{[1
,2
]}

Sainaghi, Pier Paolo ^{[2
]}

Pirisi, Mario ^{[1
,2
]}

机构：

[1] Univ Piemonte Orientale UPO, Dept Translat Med, Via Solaroli 17, I-28100 Novara, Italy

[2] AOU Maggiore Carita, Div Internal Med, Immunorheumatol Unit, Novara, Italy

来源：

ULTRAVIOLET LIGHT IN HUMAN HEALTH, DISEASES AND ENVIRONMENT | 2017年 / 996卷

关键词：

Vitamin D; Rheumatoid arthritis; Hypovitaminosis D; BONE-MINERAL DENSITY; HYPOVITAMINOSIS-D; 1,25-DIHYDROXYVITAMIN D-3; D DEFICIENCY; DISEASE-ACTIVITY; HIGH PREVALENCE; 25-HYDROXYVITAMIN D-3; PARATHYROID-HORMONE; VERTEBRAL FRACTURE; GENE-EXPRESSION;

D O I：

10.1007/978-3-319-56017-5_13

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Vitamin D is a fat soluble hormone, with a well described role in bone health and calcium/phosphate metabolism. Recent evidences have related vitamin D to other physiological functions and pathological conditions. Specifically, vitamin D has widely proven activities on immune system and evidences suggest that it may be implicated in the pathogenesis of rheumatoid arthritis (RA). The relationship between vitamin D and RA is complex, also because a deficitary vitamin D status, which is very common in RA patients, can contribute to the increased risk of osteoporosis typical of RA. In this chapter, will be described and discussed the main aspects of the relationship between RA and vitamin D.

引用

页码：155 / 168

页数：14

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