The Effects of Quercetin Supplementation on Eccentric Exercise-Induced Muscle Damage

被引:41
|
作者
Bazzucchi, Ilenia [1 ]
Patrizio, Federica [1 ]
Ceci, Roberta [2 ]
Duranti, Guglielmo [2 ]
Sgro, Paolo [3 ]
Sabatini, Stefania [2 ]
Di Luigi, Luigi [3 ]
Sacchetti, Massimo [1 ]
Felici, Francesco [1 ]
机构
[1] Univ Roma Foro Italico, Dept Movement Human & Hlth Sci, Lab Exercise Physiol, Piazza Lauro De Bosis 6, I-00135 Rome, Italy
[2] Univ Roma Foro Italico, Dept Movement Human & Hlth Sci, Lab Biochem Movement, Piazza Lauro De Bosis 6, I-00135 Rome, Italy
[3] Univ Roma Foro Italico, Dept Movement Human & Hlth Sci, Endocrinol Unit, Piazza Lauro De Bosis 6, I-00135 Rome, Italy
来源
NUTRIENTS | 2019年 / 11卷 / 01期
关键词
muscle damage; muscle weakness; electromyography; DIETARY FLAVONOID QUERCETIN; INDUCED OXIDATIVE STRESS; MITOCHONDRIAL BIOGENESIS; NEUROMUSCULAR FUNCTION; SKELETAL-MUSCLE; PERFORMANCE; ANTIOXIDANT; OXYGEN; FORCE; INFLAMMATION;
D O I
10.3390/nu11010205
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The aim of the present investigation was to test the hypothesis that quercetin (Q) may prevent the strength loss and neuromuscular impairment associated with eccentric exercise-induced muscle damage (EEIMD). Twelve young men (26.1 +/- 3.1 years) ingested either Q (1000 mg/day) or placebo (PLA) for 14 days using a randomized, double-blind, crossover study design. Participants completed a comprehensive neuromuscular (NM) evaluation before, during and after an eccentric protocol able to induce a severe muscle damage (10 sets of 10 maximal lengthening contractions). The NM evaluation comprised maximal voluntary isometric contraction (MVIC) and force-velocity relationship assessments with simultaneous recording of electromyographic signals (EMG) from the elbow flexor muscles. Soreness, resting arm angle, arm circumference, plasma creatine kinase (CK) and lactate dehydrogenase (LDH) were also assessed. Q supplementation significantly increased the isometric strength recorded during MVIC compared to baseline (+4.7%, p < 0.05). Moreover, the torque and muscle fiber conduction velocity (MFCV) decay recorded during the eccentric exercise was significant lower in Q compared to PLA. Immediately after the EEIMD, isometric strength, the force-velocity relationship and MFCV were significantly lower when participants were given PLA rather than Q. Fourteen days of Q supplementation seems able to attenuate the severity of muscle weakness caused by eccentric-induced myofibrillar disruption and sarcolemmal action potential propagation impairment.
引用
收藏
页数:13
相关论文
共 50 条
  • [1] Effects of Quercetin Supplementation on Markers of Muscle Damage and Inflammation After Eccentric Exercise
    O'Fallon, Kevin S.
    Kaushik, Diksha
    Michniak-Kohn, Bozena
    Dunne, C. Patrick
    Zambraski, Edward J.
    Clarkson, Priscilla M.
    [J]. INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, 2012, 22 (06) : 430 - 437
  • [2] The effects of creatine supplementation on exercise-induced muscle damage
    Rawson, ES
    Gunn, B
    Clarkson, PM
    [J]. JOURNAL OF STRENGTH AND CONDITIONING RESEARCH, 2001, 15 (02) : 178 - 184
  • [3] The Effects of Blueberry Supplementation on Exercise-Induced Muscle Damage
    Lee, J.
    Miller, Paul C.
    Madzima, Takudzwa A.
    [J]. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2018, 50 (05): : 721 - 722
  • [4] Effects of Flexibility Training on Eccentric Exercise-Induced Muscle Damage
    Chen, Che-Hsiu
    Nosaka, Kazunori
    Chen, Hsin-Lian
    Lin, Ming-Ju
    Tseng, Kuo-Wei
    Chen, Trevor C.
    [J]. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2011, 43 (03): : 491 - 500
  • [5] Effects Of Heating Or Cooling On Muscle Damage Measures Following Eccentric Exercise-induced Muscle Damage
    Soekmen, Buelent
    Turner, Brian
    Wilson, Dennis
    Asai, Christina
    Yonkers, Angela
    Tres, Julianne
    Spalding, Thomas
    Beam, William
    [J]. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2011, 43 (05): : 37 - 37
  • [6] RAPID ADAPTATION TO ECCENTRIC EXERCISE-INDUCED MUSCLE DAMAGE
    MAIR, J
    MAYR, M
    MULLER, E
    KOLLER, A
    HAID, C
    ARTNERDWORZAK, E
    CALZOLARI, C
    LARUE, C
    PUSCHENDORF, B
    [J]. INTERNATIONAL JOURNAL OF SPORTS MEDICINE, 1995, 16 (06) : 352 - 356
  • [7] EFFECT OF TRAINING ON ECCENTRIC EXERCISE-INDUCED MUSCLE DAMAGE
    BALNAVE, CD
    THOMPSON, MW
    [J]. JOURNAL OF APPLIED PHYSIOLOGY, 1993, 75 (04) : 1545 - 1551
  • [8] Concentric or eccentric training effect on eccentric exercise-induced muscle damage
    Nosaka, K
    Newton, M
    [J]. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2002, 34 (01): : 63 - 69
  • [9] Vitamin supplementation improves the adaptive response of skeletal muscle to repeated eccentric exercise-induced muscle damage
    Bergin, PM
    Warmington, SA
    [J]. JOURNAL OF PHYSIOLOGY-LONDON, 2002, 539 : 68P - 68P
  • [10] Effects of Eurycoma longifolia Jack supplementation on eccentric leg press exercise-induced muscle damage in rugby players
    Zakaria, Ahmad Zawawi
    Washif, Jad Adrian
    Lim, Boon Hooi
    Nosaka, Kazunori
    [J]. BIOLOGY OF SPORT, 2023, 40 (03) : 691 - 697