Human gene therapy vectors derived from feline lentiviruses

被引：20
|
作者：
Barraza, Roman A. [1 ]
Poeschla, Eric M. [1 ]
机构：
[1] Mayo Clin, Coll Med, Program Mol Med, Rochester, MN 55905 USA
来源：
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY | 2008年 / 123卷 / 1-2期
关键词：
gene therapy; retroviral vectors; feline immunodeficiency virus; innate immunity;
D O I：
10.1016/j.vetimm.2008.01.009
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Lentiviral vectors are useful for gene transfer to dividing and nondividing cells. Feline immunodeficiency virus (FIV) vectors transduce most human cell types with good efficiency and may have advantages for clinical gene therapy applications. This article reviews significant progress in the development and refinement of FIV vector systems. (C) 2008 Elsevier B.V. All rights reserved.
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收藏
页码：23 / 31
页数：9
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