Regioselective addition of silyl enolates to α, β-unsaturated aldehyde and its acetal catalyzed by MgI2 etherate

被引：0
|
作者：
Zhang, XX
Li, WDZ [1 ]
机构：
[1] Lanzhou Univ, Natl Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
[2] Lanzhou Univ, Inst Organ Chem, Lanzhou 730000, Peoples R China
来源：
CHINESE CHEMICAL LETTERS | 2003年 / 14卷 / 08期
关键词：
MgI2; etherate; silyl enolate addition; regioselective;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Regioselective addition reactions of silyl enolates to alpha, beta-unsaturated aldehyde and its acetal catalyzed by MgI2 etherate give aldol adducts (1, 2-addition) preferentially over Michael adducts (1, 4-addition). This unique regioselectivity is distinctly different with other Lewis acidic promoters and may be attributed to the high oxyphilicity of IMg+.
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页码：800 / 803
页数：4
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