A rexinoid that inhibits thymic stromal lymphopoietin (TSLP) expression and Th2 inflammation in mouse and human skin. A topical targeted-therapy concept for atopic dermatitis?

被引:0
|
作者
Tran, C. [1 ]
Milingou, M. [1 ]
Antille, C. [1 ]
Grand, D. [1 ]
Carraux, P. [1 ]
Saurat, J-H [1 ]
机构
[1] Univ Hosp Geneva, Geneva, Switzerland
关键词
D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
引用
收藏
页码:S20 / S20
页数:1
相关论文
共 12 条
  • [1] Thymic Stromal Lymphopoietin (TSLP) Modulates the Balance between Th1 and Th2 Responses in the Skin
    Larson, Ryan P.
    Ziegler, Steven F.
    JOURNAL OF IMMUNOLOGY, 2009, 182
  • [2] Thymic Stromal Lymphopoietin and Interleukin-33 Promote Skin Inflammation and Containment Of Vaccinia Virus In A Mouse Model Of Atopic Dermatitis
    Oyoshi, Michiko K.
    Beaupre, Jacqueline
    Venturelli, Nicholas
    Geha, Raif S.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 133 (02) : AB73 - AB73
  • [3] Thymic stromal lymphopoietin and IL-33 promote skin inflammation and vaccinia virus replication in a mouse model of atopic dermatitis
    Oyoshi, Michiko K.
    Venturelli, Nicholas
    Geha, Raif S.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2016, 138 (01) : 283 - 286
  • [4] Marked increase in the expression of thymic stromal lymphopoietin in the skin of atopic dermatitis mouse model by n-6 polyunsaturated fatty acid deficiency
    Fujii, Masanori
    Toda, Takahiro
    Shimazaki, Yuki
    Ohya, Susumu
    Nabe, Takeshi
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2013, 121 : 106P - 106P
  • [5] Cutting edge: Proinflammatory and Th2 cytokines synergize to induce thymic stromal lymphopoietin production by human skin keratinocytes
    Bogiatzi, Sofia I.
    Fernandez, Isabel
    Bichet, Jean-Christophe
    Marloie-Provost, Marie-Annick
    Volpe, Elisabetta
    Sastre, Xavier
    Soumelis, Vassili
    JOURNAL OF IMMUNOLOGY, 2007, 178 (06): : 3373 - 3377
  • [6] Human airway epithelial cells produce thymic stromal lymphopoietin (TSLP) after stimulation with Th2 cytokines and TLR3 ligand
    Kato, A.
    Schleimer, R. P.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 119 (01) : S161 - S161
  • [7] Mechanical injury polarizes skin dendritic cells to elicit a TH2 response by inducing cutaneous thymic stromal lymphopoietin expression
    Oyoshi, Michiko K.
    Larson, Ryan P.
    Ziegler, Steven F.
    Geha, Raif S.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2010, 126 (05) : 976 - U133
  • [8] Prostaglandin E2 (PGE2)-EP2 signaling negatively regulates murine atopic dermatitis-like skin inflammation by suppressing thymic stromal lymphopoietin expression
    Sawada, Yu
    Honda, Tetsuya
    Nakamizo, Satoshi
    Nakajima, Saeko
    Nonomura, Yumi
    Otsuka, Atsushi
    Egawa, Gyohei
    Yoshimoto, Tomohiro
    Nakamura, Motonobu
    Narumiya, Shuh
    Kabashima, Kenji
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2019, 144 (05) : 1265 - +
  • [9] Scurfy mice reveal strong autoimmune skin inflammation with Th2-deviation of skin-infiltrating CD4+T cells and high epidermal expression of thymic stromal lymphopoietin (TSLP)
    Hadaschik, E. N.
    Heckmann, B.
    Enk, A. H.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2012, 132 : S8 - S8
  • [10] Thymic stromal lymphopoietin (TSLP) is highly upregulated in epidermis of scurfy mice as a potential differentiation factor for the strong Th2-deviation in autoimmune skin inflammation of scurfy mice
    Hadaschik, E. N.
    Heckmann, B.
    Enk, A. H.
    EXPERIMENTAL DERMATOLOGY, 2012, 21 (03) : e29 - e30