Acylated oleanane-type triterpene oligoglycosides from the flower buds of Camellia sinensis var. assamica

被引:16
|
作者
Ohta, Tomoe [1 ]
Nakamura, Seikou [1 ]
Nakashima, Souichi [1 ]
Matsumoto, Takahiro [1 ]
Ogawa, Keiko [1 ]
Fujimoto, Katsuyoshi [1 ]
Fukaya, Masashi [1 ]
Yoshikawa, Masayuki [1 ]
Matsuda, Hisashi [1 ]
机构
[1] Kyoto Pharmaceut Univ, Yamashina Ku, Kyoto 6078412, Japan
基金
日本学术振兴会;
关键词
Camellia sinensis var. assamica; Theaceae; Acylated oleanane-type triterpene; Floraassamsaponin; PRUNUS-MUME; ANTIALLERGIC ACTIVITY; ALDOSE REDUCTASE; MELANOGENESIS; CONSTITUENTS; SUCROSES; GLYCOSIDES; SAPOGENOL; SAPONIN; LEAVES;
D O I
10.1016/j.tet.2014.12.049
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Eight new acylated oleanane-type triterpene oligoglycosides, floraassamsaponins I, II, III, IV, V, VI, VII, and VIII, were isolated from the flower buds of Camellia sinensis var. assamica. The chemical structures of new constituents were characterized on the basis of chemical and physicochemical evidence. In the present study, floraassamsaponins I and II with sugar moiety at 28-position were obtained from the flower buds of C. sinensis var. assamica. In the past, acylated triterpene oligoglycosides with sugar moiety at 28-position have not been isolated from the flower buds of Camellia sinensis var. sinensis. This finding is interesting from the perspective of chemotaxonomy of Camellia plants. In addition, acylated oleanane-type triterpene saponins significantly inhibited the aggregation of A beta 42. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码:846 / 851
页数:6
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