Survival of Lactobacillus rhamnosus strains in the upper gastrointestinal tract

被引：68
|
作者：
Pitino, Lole [2 ]
Randazzo, Cinzia Lucia [2 ]
Mandalari, Giuseppina [1 ,3 ]
Lo Curto, Alberto [4 ]
Faulks, Richard Martin
Le Marc, Yvan [1 ]
Bisignano, Carlo [3 ]
Caggia, Cinzia [2 ]
Wickham, Martin Sean John
机构：
[1] Inst Food Res, Foodborne Bacterial Pathogens Programme, Norwich NR4 7UA, Norfolk, England
[2] Univ Catania, DOFATA, I-95123 Catania, Italy
[3] Univ Messina, Pharmacobiol Dept, Sch Pharm, I-98168 Messina, Italy
[4] Univ Messina, Dept Pharmacochem, Sch Pharm, I-98168 Messina, Italy
来源：
FOOD MICROBIOLOGY | 2010年 / 27卷 / 08期
基金：
英国生物技术与生命科学研究理事会;
关键词：
Gastrointestinal tract; Dynamic gastric model; Probiotic; Lactobacillus rhamnosus; INTESTINAL MICROBIAL ECOSYSTEM; LACTIC-ACID BACTERIA; PROBIOTIC BACTERIA; MODULATION; GALLBLADDER; SIMULATION; PREBIOTICS; RELEASE; ECOLOGY; DISEASE;
D O I：
10.1016/j.fm.2010.07.019
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
In the present study six probiotic Lactobacillus rhamnosus strains were investigated for their ability to survive in the human upper gastrointestinal tract through a dynamic gastric model of digestion. MRS broth was used as delivery vehicle and survival was investigated during in vitro gastric and gastric plus duodenal digestion. Results highlighted that all tested strains showed good survival rate during both gastric and duodenal digestion. In particular, three strains exhibited a great survival showing a recovery percentage in the range between 117 and 276%. In agreement with survival data, high lactic acid production was detected for all strains, confirming their metabolic activity during digestion. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1121 / 1127
页数：7
相关论文
共 50 条
  • [1] Survival of Lactobacillus rhamnosus strains inoculated in cheese matrix throughout the transit in the upper gastro-intestinal tract
    Pitino, I.
    Randazzo, C. L.
    Mandalari, G.
    Faulks, R. M.
    Caggia, C.
    Wickham, M. S. J.
    [J]. JOURNAL OF BIOTECHNOLOGY, 2010, 150 : S566 - S566
  • [2] Re: Pitino et al. (2010) Food Microbiology 27:1121-1127 "Survival of Lactobacillus rhamnosus strains in the upper gastrointestinal tract"
    Zhu, Yang
    Havenaar, Robert
    Venema, Koen
    [J]. FOOD MICROBIOLOGY, 2011, 28 (05) : 1110 - 1110
  • [3] The study on the viability of lactobacillus rhamnosus in the gastrointestinal tract
    [J]. Li, Xiaodong (hrblxd@163.com), 1600, Chinese Institute of Food Science and Technology (16):
  • [4] ANTISECRETORY EFFECTS OF LACTOBACILLUS RHAMNOSUS-CONDITIONED MEDIUM PROMPTS THE NOTION OF LACTOBACILLI SPECIES AS PROBIOTICS OF THE UPPER GASTROINTESTINAL TRACT
    Padol, I. T.
    Hunt, R. H.
    [J]. GUT, 2010, 59 : A18 - A18
  • [5] Eruca sativa Might Influence the Growth, Survival under Simulated Gastrointestinal Conditions and Some Biological Features of Lactobacillus acidophilus, Lactobacillus plantarum and Lactobacillus rhamnosus Strains
    Fratianni, Florinda
    Pepe, Selenia
    Cardinale, Federica
    Granese, Tiziana
    Cozzolino, Autilia
    Coppola, Raffaele
    Nazzaro, Filomena
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2014, 15 (10) : 17790 - 17805
  • [6] Survival of Lactobacillus reuteri DSM 17938 and Lactobacillus rhamnosus GG in the Human Gastrointestinal Tract with Daily Consumption of a Low-Fat Probiotic Spread
    Dommels, Yvonne E. M.
    Kemperman, Rober A.
    Zebregs, Yvonne E. M. P.
    Draaisma, Rene B.
    Jol, Arne
    Wolvers, Danielle A. W.
    Vaughan, Elaine E.
    Albers, Ruud
    [J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2009, 75 (19) : 6198 - 6204
  • [7] Pre-cultivation with Selected Prebiotics Enhances the Survival and the Stress Response of Lactobacillus rhamnosus Strains in Simulated Gastrointestinal Transit
    Succi, Mariantonietta
    Tremonte, Patrizio
    Pannella, Gianfranco
    Tipaldi, Luca
    Cozzolino, Autilia
    Romaniello, Rossana
    Sorrentino, Elena
    Coppola, Raffaele
    [J]. FRONTIERS IN MICROBIOLOGY, 2017, 8
  • [8] Synergistic antidigestion effect of Lactobacillus rhamnosus and bovine colostrums in simulated gastrointestinal tract (in vitro)
    Wei Hua
    Xu Yang
    Xiong Yonghua
    Xu Feng
    Liu Gengpin
    [J]. Applied Microbiology and Biotechnology, 2007, 75 : 619 - 626
  • [9] Synergistic antidigestion effect of Lactobacillus rhamnosus and bovine colostrums in simulated gastrointestinal tract (in vitro)
    Wei, Hua
    Xu, Yang
    Xiong, Yonghua
    Xu, Feng
    Liu, Gengpin
    [J]. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2007, 75 (03) : 619 - +
  • [10] Dry sausage fermented by Lactobacillus rhamnosus strains
    Erkkilä, S
    Suihko, ML
    Eerola, S
    Petäjä, E
    Mattila-Sandholm, T
    [J]. INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 2001, 64 (1-2) : 205 - 210
12345