Nanogels as Contrast Agents for Molecular Imaging

被引：8
|
作者：
Zhu, Jianzhi [1 ]
Sun, Wenjie [1 ]
Shi, Xiangyang [1 ,2 ]
机构：
[1] Donghua Univ, Coll Chem Chem Engn & Biotechnol, Shanghai 201620, Peoples R China
[2] Donghua Univ, State Key Lab Modificat Chem Fibers & Polymer Mat, Shanghai 201620, Peoples R China
来源：
CHINESE JOURNAL OF CHEMISTRY | 2016年 / 34卷 / 06期
基金：
中国国家自然科学基金;
关键词：
nanogels; contrast agents; MR imaging; CT imaging; radionuclide imaging; optical imaging; dual/multi-modality imaging; IRON-OXIDE NANOPARTICLES; ENTRAPPED GOLD NANOPARTICLES; INJECTABLE COLLOIDAL GOLD; MAGNETIC-RESONANCE; DRUG-DELIVERY; IN-VIVO; HYBRID NANOGELS; BIOMEDICAL APPLICATIONS; FLUORESCENT NANOGELS; COMPUTED-TOMOGRAPHY;
D O I：
10.1002/cjoc.201500743
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Nanogels (NGs) as soft nanosized materials have gained a variety of interests in biomedical fields. The versatile NG scaffolds with 3-dimensional spherical shape, high loading efficiency, tunable surface functionalization, and excellent biocompatibility afford their uses as carrier to load mono-or multi-mode molecular imaging contrast agents (CAs). This review summarizes the synthesis routes and applications of NGs as CAs for molecular imaging applications including magnetic resonance (MR), computed tomography (CT), radionuclide, optical, and dual/ multi-modality imaging.
引用
收藏
页码：547 / 557
页数：11
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